Evidence map›Paper›PMID 32411284›Full record

ArticleComputational and mathematical methods in medicine2020

On the Chameleonic Behaviour of Cholesterol through a Fractal/Multifractal Model.

Nicolae Dan Tesloianu, Vlad Ghizdovat, Maricel Agop, Cristina Rusu, Anca Cardoneanu

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Article in Computational and mathematical methods in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nicolae Dan TesloianuCardiology Clinic, Clinical Emergency Hospital "Sf. Spiridon" Iasi, University of Medicine and Pharmacy "Gr. T. Popa", 16 University Str., Iaşi 700115, Romania.
Vlad Ghizdovat"Grigore T. Popa" University of Medicine and Pharmacy, Faculty of Medicine, Biophysics and Medical Physics Department, 16 University Str., Iaşi 700115, Romania.ORCID https://orcid.org/0000-0001-8233-8862
Maricel AgopPhysics Department, "Gheorghe Asachi" Technical University, Prof. Dr. Docent Dimitrie Mangeron Rd., No. 59A, Iaşi 700050, Romania.ORCID https://orcid.org/0000-0003-2293-5803
Cristina RusuPhysics Department, "Gheorghe Asachi" Technical University, Prof. Dr. Docent Dimitrie Mangeron Rd., No. 59A, Iaşi 700050, Romania.
Anca Cardoneanu"Grigore T. Popa" University of Medicine and Pharmacy, Faculty of Medicine, Rheumatology Department, 16 University Str., Iaşi 700115, Romania.ORCID https://orcid.org/0000-0001-9800-9289
Grigore T. Popa University of Medicine and Pharmacy · ROAcademia Oamenilor de Știință din România · ROGheorghe Asachi Technical University of Iași · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing number of studies are beginning to show that both low-density lipoprotein and high-density lipoprotein cholesterol can constitute risk factors for myocardial infarction. Such a behaviour has been called by experts in the field the "chameleonic effect" of cholesterol. In the present paper, a fractal/multifractal model for low-density lipoprotein and high-density lipoprotein cholesterol dynamics is proposed. In such a context, a fractal/multifractal tunneling effect for systems with spontaneous symmetry breaking is analyzed so that if the spontaneous symmetry breaking is assimilated to an inflammation (in the form of a specific scalar potential), then a coupling between two fractal/multifractal states can be observed. These two states, which have been associated to biological structures such as low-density lipoprotein and high-density lipoprotein, transfer their states through a fractal/multifractal tunneling effect. Moreover, in our opinion, the widely used notions of "good" and "bad" cholesterol must be redefined as two different states (low-density lipoprotein and high-density lipoprotein) of the same biological structure named "cholesterol." In our work, for the first time in the specialized literature, low-density lipoprotein and high-density lipoprotein have been regarded as two different states of the same biological structure (named "cholesterol"), such as in nuclear physics, the neutron and proton are two different states of the same particle named nucleon.

Indexed as

Models, BiologicalBiomarkersCausalityCholesterolCholesterol, HDLCholesterol, LDLComputational BiologyFemaleFractalsHumansInflammationMaleMathematical ConceptsMyocardial InfarctionNonlinear DynamicsRisk FactorsBiomarkersCholesterolCholesterol, HDLCholesterol, LDL

Identifiers

PMID32411284
PMCPMC7199616
OpenAlexW2997824257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.