Evidence map›Paper›PMID 32411197›Full record

ArticleGastroenterology research and practice2020

Treatment Adherence in Inflammatory Bowel Disease Patients from Argentina: A Multicenter Study.

Juan Lasa, Gustavo Correa, Claudia Fuxman, Laura Garbi, Maria Eugenia Linares, Pablo Lubrano, Astrid Rausch, Martin Toro, Martin Yantorno, Ignacio Zubiaurre and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Gastroenterology research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04893928 (Role of Information and Communication Technologies for Health Support in Inflammatory Bowel Diseases), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04893928 unknown statusnot on this mapstarted 2021, after this paper: background citation

Role of Information and Communication Technologies for Health Support in Inflammatory Bowel Diseases: The DAMASCO Trial (Stage I)

TypeobservationalSponsorHospital Nacional Profesor Alejandro PosadasRan2021 to 2022Enrolled351ConditionsInflammatory Bowel Diseases, Knowledge, Attitudes, Practice, Quality of Life, Treatment Adherence and ComplianceArmsQUECOMIICAT survey, Self-Efficacy for Appropriate Medication Use Scale, ICTs preferences and barriers survey, Focus group and IBD mobile App for health support (MAHS) development and validation
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juan LasaGastroenterology Department, Hospital Britanico de Buenos Aires, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-0957-5591
Gustavo CorreaGastroenterology Department, Hospital Interzonal General de Agudos "General José de San Martín", La Plata, Argentina.ORCID https://orcid.org/0000-0003-3827-8158
Claudia FuxmanGastroenterology Department, Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-6264-937X
Laura GarbiGastroenterology Department, Hospital Interzonal General de Agudos "General José de San Martín", La Plata, Argentina.
Maria Eugenia LinaresGastroenterology Department, Hospital de Clínicas "José de San Martín", Buenos Aires, Argentina.ORCID https://orcid.org/0000-0001-8870-4624
Pablo LubranoGastroenterology Department, Sanatorio Mater Dei, Buenos Aires, Argentina.
Astrid RauschGastroenterology Department, Hospital Britanico de Buenos Aires, Buenos Aires, Argentina.
Martin ToroGastroenterology Department, Hospital Universitario, Universidad Nacional de Cuyo, Mendoza, Argentina.
Martin YantornoGastroenterology Department, Hospital Interzonal General de Agudos "General José de San Martín", La Plata, Argentina.ORCID https://orcid.org/0000-0002-6123-7103
Ignacio ZubiaurreGastroenterology Department, Hospital Britanico de Buenos Aires, Buenos Aires, Argentina.
Laurent Peyrin-BirouletINSERM U954 and Department of Hepatogastroenterology, Nancy University Hospital, Université de Lorraine, Vandoeuvre-lès-Nancy, France.
Pablo OliveraGastroenterology Section, Department of Internal Medicine, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsA multicenter cross-sectional study involving seven referral centers from three cities of Argentina was undertaken. Patients with a diagnosis of ulcerative colitis (UC), Crohn's disease (CD), or indeterminate colitis (IBDU/IC) were invited to answer an anonymous survey, which included a 5-point Likert scale to evaluate adherence to therapies. Independent variables associated with inadequate adherence were evaluated.

resultsOverall, 447 UC/IBDU and 135 CD patients were enrolled. Median age was 37 years (range 21-72); 39.8% were male; median time from diagnosis was 6 years (0.5-35). 91.4% were under treatment with at least one oral medication; 50.3% of patients reported inadequate adherence to oral medications. Patients with UC/IBDU had a lower risk of inadequate adherence when compared to patients with CD (OR 0.57 (0.37-0.87)). 21.8% reported inadequate adherence to biologics; subcutaneous administration was significantly associated with inadequate adherence to biologics (OR 4.8 (1.57-14.66)).

conclusionInadequate treatment adherence is common among patients with IBD, and potentially modifiable factors were identified.

Identifiers

PMID32411197
PMCPMC7201740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.