Evidence map›Paper›PMID 32411135›Full record

ArticleFrontiers in immunology2020

Xiangguo Duan, Peng Sun, Yaru Lan, Chunxiu Shen, Xiaoyu Zhang, Shaozhang Hou, Jian Chen, Bin Ma, Yuhan Xia, Chunxia Su

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Inside-out assembly of viral antigens for the enhanced vaccination.Signal transduction and targeted therapy · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xiangguo DuanDepartment of Laboratory Medicine, College of Clinical Medicine, Ningxia Medical University, Yinchuan, China.
Peng SunSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China.
Yaru LanSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China.
Chunxiu ShenSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China.
Xiaoyu ZhangSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China.
Shaozhang HouSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China.
Jian ChenGuolong Hospital, Yinchuan, China.
Bin MaDepartment of Oncology Surgery, The First People's Hospital of Yinchuan, Yinchuan, China.
Yuhan XiaGeneral Hospital of Ningxia Medical University, Yinchuan, China.
Chunxia SuSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China.
Ningxia Medical University · CNNingxia Medical University General Hospital · CNYinchuan First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular helper T (Tfh) cells regulate high-affinity antibody production. Some findings have indicated that Tfh cells could be differentiated into memory cells. Here we have investigated the effects of IFN-α, as an adjuvant, on the generation of memory Tfh cell and memory B cell responses. The data showed that adenoviral vectors expressing: (i) foot-and-mouth disease virus (FMDV) VP1 proteins and porcine IFN-α, or (ii) porcine IFN-α alone, potently enhanced the generation of memory Tfh cells, especially the CCR7

Indexed as

AdenoviridaeAdenovirus VaccinesAdjuvants, ImmunologicAnimalsB-LymphocytesCapsid ProteinsFemaleFoot-and-Mouth DiseaseFoot-and-Mouth Disease VirusGenetic VectorsImmunologic MemoryInterferon-alphaMiceMice, Inbred BALB CT Follicular Helper CellsVaccinationAdenovirus VaccinesAdjuvants, ImmunologicCapsid ProteinsInterferon-alphaVaccines, SyntheticVP1 protein, Foot-and-mouth disease virusfoot-and-mouth disease recombinant adenovirus vaccineIFN-αimmune memorymemory B cellmemory Tfh cell

Identifiers

PMID32411135
PMCPMC7200983
OpenAlexW3015604504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.