Evidence map›Paper›PMID 32411131›Full record

ArticleFrontiers in immunology2020

Antibiotic Treatment Shapes the Antigenic Environment During Chronic TB Infection, Offering Novel Targets for Therapeutic Vaccination.

Yu-Min Chuang, Noton K Dutta, James T Gordy, Victoria L Campodónico, Michael L Pinn, Richard B Markham, Chien-Fu Hung, Petros C Karakousis

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. MIP3α-RelVaccine · 2025
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  5. Review
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  9. Pathological and protective roles of dendritic cells inFrontiers in cellular and infection microbiology · 2022
    Review
  10. Targeting theFrontiers in microbiology · 2021
    Review
  11. Enhancement of CD4Frontiers in cellular and infection microbiology · 2021
    Article
  12. One Size Fits All? Not inFrontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yu-Min ChuangDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Noton K DuttaDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
James T GordyW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Victoria L CampodónicoDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Michael L PinnDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Richard B MarkhamW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Chien-Fu HungDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Petros C KarakousisDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Mentoring in Immunometabolic Dysregulation in TB and TB/HIVK24AI143447 · NIAID · JOHNS HOPKINS UNIVERSITY · PI KARAKOUSIS, PETROS C · 2019 to 2024
$956k
NIAID NIH HHS K24 AI143447
6 · The paper itself

Abstract

The lengthy and complicated current regimen required to treat drug-susceptible tuberculosis (TB) reflects the ability of

Indexed as

AnimalsAntigens, BacterialAntitubercular AgentsBacterial ProteinsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell LineChronic DiseaseDrug Resistance, BacterialFemaleGuanosine PentaphosphateGuinea PigsHydrolasesIsoniazidLigasesMacrophagesAntigens, BacterialAntitubercular AgentsBacterial ProteinsESAT-6 protein, Mycobacterium tuberculosisGuanosine PentaphosphateHydrolasesIsoniazidLigasesTB10.4 antigen, Mycobacterium tuberculosisTuberculosis VaccinesVaccines, DNAimmunotherapyMycobacterium tuberculosispersistencestringent responsetuberculosis DNA vaccines

Identifiers

PMID32411131
PMCPMC7198710
OpenAlexW3020876442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.