Evidence map›Paper›PMID 32410980›Full record

ArticleFrontiers in aging neuroscience2020

Insula and Amygdala Atrophy Are Associated With Functional Impairment in Subjects With Presbycusis.

Chama Belkhiria, Rodrigo C Vergara, Simón San Martin, Alexis Leiva, Melissa Martinez, Bruno Marcenaro, Maricarmen Andrade, Paul H Delano, Carolina Delgado

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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  9. [Relationship Between Hearing Loss and Cognitive Function in Elderly Chinese People: A Study Based on Propensity Score Matching].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Chama BelkhiriaNeuroscience Department, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Rodrigo C VergaraNeuroscience Department, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Simón San MartinNeuroscience Department, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Alexis LeivaNeuroscience Department, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Melissa MartinezNeurology and Neurosurgery Department, Hospital Clínico de la Universidad de Chile, Santiago, Chile.
Bruno MarcenaroNeuroscience Department, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Maricarmen AndradeInternal Medicine Department, Clínica Universidad de los Andes, Santiago, Chile.
Paul H DelanoNeuroscience Department, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Carolina DelgadoNeuroscience Department, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
University of Chile · CLHospital Clínico de la Universidad de Chile · CLMetropolitan University of Educational Sciences · CLUniversidad de Los Andes, Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hearing loss is an important risk factor for dementia. However, the mechanisms that relate these disorders are still unknown. As a proxy of this relationship, we studied the structural brain changes associated with functional impairment in activities of daily living in subjects with age related hearing loss, or presbycusis. One hundred eleven independent, non-demented subjects older than 65 years recruited in the ANDES cohort were evaluated using a combined approach including (i) audiological tests: hearing thresholds and cochlear function measured by pure tone averages and the distortion product otoacoustic emissions respectively; (ii) behavioral variables: cognitive, neuropsychiatric, and functional impairment in activities of daily living measured by validated questionnaires; and (iii) structural brain imaging-assessed by magnetic resonance imaging at 3 Tesla. The mean age of the recruited subjects (69 females) was 73.95 ± 5.47 years (mean ± SD) with an average educational level of 9.44 ± 4.2 years of schooling. According to the audiometric hearing thresholds and presence of otoacoustic emissions, we studied three groups: controls with normal hearing (

Indexed as

activities of daily livingapathybehavioral impairmentcochlear dysfunctiondementiainsula atrophypresbycusis

Identifiers

PMID32410980
PMCPMC7198897
OpenAlexW3022364533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.