Evidence map›Paper›PMID 32410947›Full record

ArticleFrontiers in neuroscience2020

The Effect of Side of Implantation on the Cortical Processing of Frequency Changes in Adult Cochlear Implant Users.

Chun Liang, Lisa H Wenstrup, Ravi N Samy, Jing Xiang, Fawen Zhang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00600717 (Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00600717 withdrawnnot on this map

Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals

TypeobservationalSponsorChildren's Hospital Medical Center, CincinnatiRan2000 to 2027Enrolled0ConditionsEpilepsy, Migraine, Headache, Pain
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. The Best Users of Cochlear Implants.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chun LiangDepartment of Communication Sciences and Disorders, University of Cincinnati, Cincinnati, OH, United States.
Lisa H WenstrupDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, United States.
Ravi N SamyDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, United States.
Jing XiangDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Fawen ZhangDepartment of Communication Sciences and Disorders, University of Cincinnati, Cincinnati, OH, United States.
University of Cincinnati · USCincinnati Children's Hospital Medical Center · US

Funding

Cortical processing of frequency changes in cochlear implant usersR15DC016463 · NIDCD · UNIVERSITY OF CINCINNATI · PI ZHANG, FAWEN · 2017 to 2017
$445k
NIDCD NIH HHS R15 DC016463
6 · The paper itself

Abstract

Cochlear implants (CI) are widely used in children and adults to restore hearing function. However, CI outcomes are vary widely. The affected factors have not been well understood. It is well known that the right and left hemispheres play different roles in auditory perception in adult normal hearing listeners. It is unknown how the implantation side may affect the outcomes of CIs. In this study, the effect of the implantation side on how the brain processes frequency changes within a sound was examined in 12 right-handed adult CI users. The outcomes of CIs were assessed with behaviorally measured frequency change detection threshold (FCDT), which has been reported to significantly affect CI speech performance. The brain activation and regions were also examined using acoustic change complex (ACC, a type of cortical potential evoked by acoustic changes within a stimulus), on which the waveform analysis and the standardized low-resolution brain electromagnetic tomography (sLORETA) were performed. CI users showed activation in the temporal lobe and non-temporal areas, such as the frontal lobe. Right-ear CIs could more efficiently activate the contralateral hemisphere compared to left-ear CIs. For right-ear CIs, the increased activation in the contralateral temporal lobe together with the decreased activation in the contralateral frontal lobe was correlated with good performance of frequency change detection (lower FCDTs). Such a trend was not found in left-ear CIs. These results suggest that the implantation side may significantly affect neuroplasticity patterns in adults.

Indexed as

acoustic change complexcochlear implantfrequency change detectionfrontal lobestandardized low-resolution brain electromagnetic tomography (sLORETA)temporal lobe

Identifiers

PMID32410947
PMCPMC7201306
OpenAlexW3023981286

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.