Evidence map›Paper›PMID 32410915›Full record

ArticleJournal of interventional cardiology2020

Everolimus-Eluting Biodegradable Abluminal Coating Stent versus Durable Conformal Coating Stent: Termination of the Inflammatory Response Associated with Neointimal Healing in a Porcine Coronary Model.

Masayuki Mori, Kenji Sakata, Junichiro Yokawa, Chiaki Nakanishi, Kota Murai, Hirofumi Okada, Masaya Shimojima, Shohei Yoshida, Kazuaki Yoshioka, Yoh Takuwa and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of interventional cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Masayuki MoriDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Kenji SakataDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.ORCID https://orcid.org/0000-0002-6312-8912
Junichiro YokawaDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Chiaki NakanishiDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Kota MuraiDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Hirofumi OkadaDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Masaya ShimojimaDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Shohei YoshidaDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Kazuaki YoshiokaDepartment of Molecular Vascular Physiology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Yoh TakuwaDepartment of Molecular Vascular Physiology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Kenshi HayashiDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Masakazu YamagishiOsaka University of Human Sciences, Osaka, Japan.
Masa-Aki KawashiriDepartment of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Kanazawa University · JPOsaka University of Human Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe evaluated the effect of the different carrier systems on early vascular response through histological analysis and scanning electron microscopy using a porcine model.

backgroundAlthough Synergy™ and Promus PREMIER™ share an identical stent material and drug elution (everolimus), they use different drug carrier systems: biodegradable abluminal coating polymer or durable conformal coating polymer, respectively. However, data regarding the impact of the different coating systems on vessel healing are currently limited.

methodsTwelve Synergy™ and Promus PREMIER™ were implanted in 12 swine. Histopathological analysis of the stented segments was performed on the 2

resultsOn the 2

conclusionsThese results demonstrate that termination of reactive inflammation is accelerated after abluminal coating stent versus implantation of conformal coating stent.

Indexed as

Coronary VesselsDrug-Eluting StentsAbsorbable ImplantsAnimalsCoated Materials, BiocompatibleDrug CarriersEverolimusInflammationModels, AnatomicNeointimaPolymersStentsSwineVascular GraftingCoated Materials, BiocompatibleDrug CarriersEverolimusPolymers

Identifiers

PMID32410915
PMCPMC7201493
OpenAlexW3018683323

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.