Evidence map›Paper›PMID 32410904›Full record

ArticleInternational journal of MS care

Prevalence of Lower Urinary Tract Symptoms in People with Multiple Sclerosis: A Systematic Review and Meta-analysis.

Hawra B Al Dandan, Susan Coote, Doreen McClurg

4 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in International journal of MS care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05075642 unknown statusnot on this map

A Multicentre Observational Study for the Evaluation in Clinical Practice of the Initial Diagnostic-therapeutic Path of Urinary Disorders in Multiple Sclerosis

TypeobservationalSponsorASP 7 RagusaRan2021 to 2023Enrolled214ConditionsMultiple Sclerosis, Urinary Bladder, NeurogenicArmsInitial management of the urinary disorder/s identified during the screening phase
NCT06226831 unknown statusnot on this map

Onset of Lower Urinary Tract Symptoms in Multiple Sclerosis Patients

TypeobservationalSponsorUniversity Hospital OstravaRan2020 to 2025Enrolled1,500ConditionsLower Urinary Tract Symptoms, Multiple SclerosisArmsStructured interview
NCT06581341 nanot yet recruitingnot on this map

Improvement of Pelvic Floor Function Using Repetitive Transcranial Magnetic Stimulation and Posterior Tibial Nerve Stimulation in Treating Neurogenic Overactive Bladder in Patients With Multiple Sclerosis

TypeinterventionalSponsorSierra Varona SLRan2024 to 2025Enrolled60ConditionsNeurogenic Overactive Bladder, Multiple SclerosisArmsRepetitive Transcranial Magnetic Stimulation and Percutaneous Tibial Nerve Stimulation, Repetitive Transcranial Magnetic Stimulation, Percutaneous Tibial Nerve Stimulation
NCT07183683 narecruitingnot on this map

Electrical Versus Manual Stimulation of Acupuncture Points in Female Patients With Multiple Sclerosis and Neurogenic Bladder Dysfunction - A Pragmatic, Exploratory, Three-Arm, Randomized Controlled Trial Using a Mixed Methods Approach

TypeinterventionalSponsorCharite University, Berlin, GermanyRan2025 to 2027Enrolled150ConditionsNeurogenic Bladder DysfunctionArmsgroup 1: electrical stimulation of acupuncture points plus routine care, group 2: acupressure plus routine care
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Prevalence of stress urinary incontinence and urge urinary incontinence in multiples sclerosis patients: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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  9. Association between lower urinary tract symptoms on quality of life in women with multiple sclerosis: The mediating role of loneliness.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  14. Frailty and urinary symptoms share pathophysiological mechanisms involved in disease progression in people with multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hawra B Al Dandan
Susan Coote
Doreen McClurg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNo published study, to our knowledge, has systematically reviewed the prevalence estimates of lower urinary tract symptoms (LUTSs) and LUTS types in the general multiple sclerosis (MS) population. Therefore, a systematic review and a meta-analysis were conducted to determine the totality of literature investigating the prevalence of LUTSs and LUTS types in the general MS population according to International Continence Society definitions.

methodsVarious electronic databases were searched between January 4, 2018, and February 12, 2018. This review included observational studies involving adults (18 years or older) with a confirmed diagnosis of MS recruited from the general MS population using self-report and/or objective outcome measures for LUTSs.

resultsTwelve studies were included in the meta-analysis. The results showed that LUTSs were prevalent in people with MS, with a pooled prevalence of 68.41% using self-report and 63.95% using the objective measure of urodynamics. When considering LUTS types, urinary frequency was the predominant symptom, with a pooled prevalence estimate of 73.45%, followed by urgency assessed using self-report measures at 63.87%. Detrusor overactivity was found to be the most prevalent urodynamic symptom, with a pooled prevalence estimate of 42.9%, followed by detrusor sphincter dyssynergia at 35.44%.

conclusionsThis systematic review revealed that LUTSs are highly prevalent in MS. There is a need for improvement in the conduct and reporting of prevalence studies of LUTSs in MS and for the use of validated self-report outcome measures to enable pooling of data in the future.

Indexed as

Multiple sclerosis (MS)Neurogenic bladderOveractive bladderUrinary tract symptoms

Identifiers

PMID32410904
PMCPMC7204365
OpenAlexW3019502469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.