Evidence map›Paper›PMID 32410857›Full record

ArticleMediators of inflammation2020

Association of Brain-Gut Peptides with Inflammatory Cytokines in Moyamoya Disease.

Wenxiu Han, Feng Jin, Hailiang Zhang, Mengqi Yang, Changmeng Cui, Changshui Wang, Pei Jiang

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wenxiu HanJining First People's Hospital, Jining Medical University, Jining, China.
Feng JinAffiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.ORCID https://orcid.org/0000-0002-6558-9405
Hailiang ZhangJining First People's Hospital, Jining Medical University, Jining, China.
Mengqi YangJining First People's Hospital, Jining Medical University, Jining, China.
Changmeng CuiAffiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.ORCID https://orcid.org/0000-0001-9038-0673
Changshui WangDepartment of Clinical Translational Medicine, Jining Life Science Center, Jining, China.
Pei JiangJining First People's Hospital, Jining Medical University, Jining, China.ORCID https://orcid.org/0000-0002-8360-7427
Jining First People's Hospital · CNAffiliated Hospital of Jining Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic inflammation has been shown to play a pivotal role in the pathogenesis of moyamoya disease (MMD). Brain-gut peptides exhibit regulatory effects in the secretion of proinflammatory cytokines. To investigate the association between brain-gut peptides and inflammation in the occurrence of MMD, 41 patients with MMD, as well as 74 age- and sex-matched healthy individuals were enrolled. The levels of four brain-gut peptides (vasoactive intestinal polypeptide (VIP), cholecystokinin (CCK), somatostatin (SST), substance P (SP)) and three proinflammatory cytokines (interleukin-1

Indexed as

Gastrointestinal MicrobiomeAdultBiomarkersBrainCase-Control StudiesCytokinesFemaleHumansInflammationIntestinesMaleMiddle AgedMoyamoya DiseasePeptidesRegression AnalysisROC CurveBiomarkersCytokinesPeptidesTumor Necrosis Factor-alphaVasoactive Intestinal Peptide

Identifiers

PMID32410857
PMCPMC7204157
OpenAlexW3023415844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.