Evidence map›Paper›PMID 32410672›Full record

ReviewTheoretical biology & medical modelling2020

Computational models of melanoma.

Marco Albrecht, Philippe Lucarelli, Dagmar Kulms, Thomas Sauter

Abstract readReview
In one paragraph

Review in Theoretical biology & medical modelling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marco AlbrechtSystems Biology Group, Life Science Research Unit, University of Luxembourg, 6, avenue du Swing, Belval, 4367, Luxembourg.
Philippe LucarelliSystems Biology Group, Life Science Research Unit, University of Luxembourg, 6, avenue du Swing, Belval, 4367, Luxembourg.
Dagmar KulmsExperimental Dermatology, Department of Dermatology, Dresden University of Technology, Fetscherstraße 105, Dresden, 01307, Germany.
Thomas SauterSystems Biology Group, Life Science Research Unit, University of Luxembourg, 6, avenue du Swing, Belval, 4367, Luxembourg. thomas.sauter@uni.lu.ORCID 0000-0001-8225-2954

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genes, proteins, or cells influence each other and consequently create patterns, which can be increasingly better observed by experimental biology and medicine. Thereby, descriptive methods of statistics and bioinformatics sharpen and structure our perception. However, additionally considering the interconnectivity between biological elements promises a deeper and more coherent understanding of melanoma. For instance, integrative network-based tools and well-grounded inductive in silico research reveal disease mechanisms, stratify patients, and support treatment individualization. This review gives an overview of different modeling techniques beyond statistics, shows how different strategies align with the respective medical biology, and identifies possible areas of new computational melanoma research.

Indexed as

Computer SimulationGene Regulatory NetworksMelanomaSkin NeoplasmsComputational BiologyHumansModels, BiologicalProteinsProteinsMelanomaPhysical oncologySystems biologyTumor growth

Identifiers

PMID32410672
PMCPMC7222475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.