Evidence map›Paper›PMID 32410442›Full record

ArticleBiochemistry2020

Dimeric Stilbene Antibiotics Target the Bacterial Cell Wall in Drug-Resistant Gram-Positive Pathogens.

Tyler N Goddard, Jaymin Patel, Hyun Bong Park, Jason M Crawford

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tyler N GoddardDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
Jaymin PatelChemical Biology Institute, Yale University, West Haven, Connecticut 06516, United States.ORCID 0000-0002-4380-4805
Hyun Bong ParkDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.ORCID 0000-0002-2986-3833
Jason M CrawfordDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.ORCID 0000-0002-7583-1242
Yale University · US

Funding

Predoc Training at the Interface Chemistry and BiologyT32GM067543 · NIGMS · YALE UNIVERSITY · PI CRAWFORD, JASON MICHAEL · 2003 to 2022
$7.4M
Cryptic gut bacterial metabolites that regulate colorectal cancer formationDP2CA186575 · NCI · YALE UNIVERSITY · PI CRAWFORD, JASON MICHAEL · 2013 to 2013
$2.5M
Ecological triggers to exploit antibiotic and virulence factor regulationR00GM097096 · NIGMS · YALE UNIVERSITY · PI CRAWFORD, JASON MICHAEL · 2012 to 2014
$721k
EPA EP-W-17-011NCI NIH HHS DP2 CA186575NIGMS NIH HHS R00 GM097096NIGMS NIH HHS T32 GM067543
6 · The paper itself

Abstract

The prevalence of antibiotic resistance has been increasing globally, and new antimicrobial agents are needed to address this growing problem. We previously reported that a stilbene dimer from

Indexed as

Anti-Bacterial AgentsCell WallDrug Resistance, BacterialEnterococcus faeciumHumansMethicillinMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMolecular StructureStilbenesVancomycinAnti-Bacterial AgentsMethicillinStilbenesVancomycin

Identifiers

PMID32410442
PMCPMC10578317
OpenAlexW3024136946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.