ArticleKorean journal of radiology2020
Twelve-Month Volume Reduction Ratio Predicts Regrowth and Time to Regrowth in Thyroid Nodules Submitted to Laser Ablation: A 5-Year Follow-Up Retrospective Study.
Article in Korean journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Long-term clinical outcomes of thermal ablation for benign thyroid nodules and unresolved issues: a comprehensive systematic review.La Radiologia medica · 2025Pooled it
- Efficacy of radiofrequency and laser thermal ablation in solving thyroid nodule-related symptoms and cosmetic concerns. A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2022Pooled it
- Microwave ablation for low-risk papillary thyroid microcarcinoma: efficacy, safety, and prognostic factors.Gland surgery · 2026Article
- Machine learning-based ultrasound radiomics for prediction of 6-month local thermal ablation response in benign thyroid nodules: a multicenter study.Frontiers in endocrinology · 2026Article
- Evolving patient preferences from surgery to thermal ablation in solitary thyroid nodule treatment.Scientific reports · 2025Article
- Predicting the efficacy of microwave ablation of benign thyroid nodules from ultrasound images using deep convolutional neural networks.BMC medical informatics and decision making · 2025Article
- Review
- Assessing the impact of malignant thyroid nodules on the efficacy of radiofrequency ablation: a single-center prospective study.Frontiers in endocrinology · 2025Article
- Laser ablation for spongiform thyroid nodules: identifying baseline nodule volume and energy to be delivered for successful treatment.Endocrine · 2024Article
- A 6-year single-center prospective follow-up study of the efficacy of radiofrequency ablation for thyroid nodules.Frontiers in endocrinology · 2024Article
- Laser Ablation for Benign and Malignant Thyroid Nodules - A Mini-Literature Review.Endocrine, metabolic & immune disorders drug targets · 2024Review
- General Principles for the Safe Performance, Training, and Adoption of Ablation Techniques for Benign Thyroid Nodules: An American Thyroid Association Statement.Thyroid : official journal of the American Thyroid Association · 2023Article
- [Clinical Approach for Thyroid Radiofrequency Ablation].Journal of the Korean Society of Radiology · 2023Review
- Analysis and prediction of regrowth in benign thyroid nodules undergoing radiofrequency ablation: a retrospective study with a 5-year follow-up.European radiology · 2023Article
- Outcomes of laser-induced thermotherapy for thyroid nodules at the West Vascular Center, Ukraine.Journal of medicine and life · 2023Article
- Long-term follow-up of the radiofrequency ablation of benign thyroid nodules: the value of additional treatment.Ultrasonography (Seoul, Korea) · 2022Article
- How to Clearly and Accurately Report Odds Ratio and Hazard Ratio in Diagnostic Research Studies?Korean journal of radiology · 2022Article
- Additional treatment of recurrent or regrowing cystic thyroid nodules after ethanol ablation.Ultrasonography (Seoul, Korea) · 2021Article
- Unresolved Clinical Issues in Thermal Ablation of Benign Thyroid Nodules: Regrowth at Long-Term Follow-Up.Korean journal of radiology · 2021Article
- Percutaneous Ultrasound-Guided Laser Ablation of Benign Thyroid Nodules: Results of 10-Year Follow-Up in 171 Patients.Journal of the Endocrine Society · 2021Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveLaser ablation is a therapeutic modality used to reduce the volume of large benign thyroid nodules. Unsatisfactory reduction and regrowth are observed in some treated nodules. The aim of the study was to evaluate the long-term outcomes of laser treatment for solid nodules during a 5-year follow-up period, the regrowth rate, and the predictive risk factors of nodule regrowth. MATERIALS AND
methodsWe retrospectively evaluated patients with benign, solid, cold thyroid nodules who underwent laser ablation and were followed-up for 5 years. According to the selection criteria, 104 patients were included (median baseline nodule volume, 12.5 mL [25.0-75.0%, 8-18 mL]; median energy delivered, 481.5 J/mL [25.0-75.0%, 370-620 J/mL]). Nodule volume, thyroid function test results, and ultrasound were evaluated at baseline and then annually after the procedure.
resultsOf 104 patients, 31 patients (29.8%) had a 12-month volume reduction ratio (VRR) < 50.0% and 39 (37.5%) experienced nodule regrowth. Of these 39 patients, 17 (43.6%) underwent surgery and 14 (35.9%) underwent a second laser treatment. The rate of nodule regrowth was inversely related to the 12-month VRR, i.e., the lower the 12-month VRR, the higher the risk of regrowth (
conclusionThe VRR of thyroid nodules subjected to similar amounts of laser energy varies widely and depends on the nodule composition; non-spongiform nodules are reduced to a lesser extent and regrow more frequently than spongiform nodules. A 12-month VRR < 50.0% is a predictive risk factor for regrowth and correlates with the time to regrowth.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.