Evidence map›Paper›PMID 32410407›Full record

SynthesisKorean journal of radiology2020

The Diagnostic Performance of the Length of Tumor Capsular Contact on MRI for Detecting Prostate Cancer Extraprostatic Extension: A Systematic Review and Meta-Analysis.

Tae Hyung Kim, Sungmin Woo, Sangwon Han, Chong Hyun Suh, Soleen Ghafoor, Hedvig Hricak, Hebert Alberto Vargas

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Korean journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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  19. Early biomarkers of extracapsular extension of prostate cancer using MRI-derived semantic features.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Tae Hyung KimDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0002-0333-8475
Sungmin WooDepartment of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. woos@mskcc.org.ORCID 0000-0001-8459-8369
Sangwon HanDepartment of Nuclear Medicine, Armed Forces Daejeon Hospital, Daejeon, Korea.ORCID 0000-0001-8095-0396
Chong Hyun SuhDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, Seoul, Korea.ORCID 0000-0002-4737-0530
Soleen GhafoorDepartment of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-8459-7363
Hedvig HricakDepartment of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.ORCID 0000-0003-2240-9694
Hebert Alberto VargasDepartment of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.ORCID 0000-0003-1169-133X
Memorial Sloan Kettering Cancer Center · USArmed Forces Capital Hospital · KRAsan Medical Center · KRSeoul National University · KR

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectiveThe purpose was to review the diagnostic performance of the length of tumor capsular contact (LCC) on magnetic resonance imaging (MRI) for detecting prostate cancer extraprostatic extension (EPE). MATERIALS AND

methodsPubMed and EMBASE databases were searched up to March 24, 2019. We included diagnostic accuracy studies that evaluated LCC on MRI for EPE detection using radical prostatectomy specimen histopathology as the reference standard. Quality of studies was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. Sensitivity and specificity were pooled and graphically presented using hierarchical summary receiver operating characteristic (HSROC) plots. Meta-regression and subgroup analyses were conducted to explore heterogeneity.

resultsThirteen articles with 2136 patients were included. Study quality was generally good. Summary sensitivity and specificity were 0.79 (95% confidence interval [CI] 0.73-0.83) and 0.67 (95% CI 0.60-0.74), respectively. Area under the HSROC was 0.81 (95% CI 0.77-0.84). Substantial heterogeneity was present among the included studies according to Cochran's Q-test (

conclusionGreater LCC on MRI is associated with a higher probability of prostate cancer EPE. Due to heterogeneity among the studies, further investigation is needed to establish the optimal cutoff value for each clinical setting.

Indexed as

Magnetic Resonance ImagingArea Under CurveHumansMaleNeoplasm GradingProstatic NeoplasmsROC CurveSensitivity and SpecificityMagnetic resonance imagingMeta-analysisProstate cancerSystematic review

Identifiers

PMID32410407
PMCPMC7231615
OpenAlexW3021015509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.