Evidence map›Paper›PMID 32410329›Full record

ArticlePediatric diabetes2020

Prevalence of diabetic retinopathy in children and adolescents at an urban tertiary eye care center.

Mark Porter, Roomasa Channa, Jessica Wagner, Laura Prichett, Tin Yan Alvin Liu, Risa M Wolf

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Pediatric diabetes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05463289 (Implementing Digital Retinal Exams Into Comprehensive Pediatric Diabetes Care), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05463289 narecruitingnot on this mapstarted 2022, after this paper: background citation

Implementing Digital Retinal Exams Into Comprehensive Pediatric Diabetes Care

TypeinterventionalSponsorJohns Hopkins UniversityRan2022 to 2026Enrolled500ConditionsType 1 Diabetes, Type 2 Diabetes, Cystic Fibrosis-related DiabetesArmsPoint of Care Autonomous AI diabetic retinopathy exam
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Early Retinal Changes Detected Using Optical Coherence Tomography Angiography in Youth with Type 1 Diabetes Mellitus: A Case-Control Study.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2026
    Article
  4. Article
  5. Article
  6. Improving Diabetes-Related Retinopathy Screening and Documentation in Youth With Diabetes.Clinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  7. Review
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mark PorterPediatric Endocrine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-0820-1232
Roomasa ChannaOphthalmology, Wilmer Eye Institute at the Johns Hopkins University, Baltimore, Maryland, USA.
Jessica WagnerEpidemiology and Data Management (BEAD) Core, Johns Hopkins School of Medicine Biostatistics, Baltimore, Maryland, USA.
Laura PrichettEpidemiology and Data Management (BEAD) Core, Johns Hopkins School of Medicine Biostatistics, Baltimore, Maryland, USA.
Tin Yan Alvin LiuOphthalmology, Wilmer Eye Institute at the Johns Hopkins University, Baltimore, Maryland, USA.
Risa M WolfPediatric Endocrine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-7674-520X
Johns Hopkins University · US

Funding

Clinical Research&Epidemiology in Diabetes&EndocrinologyT32DK062707 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Wendy Lynet Bennett · 2002 to 2026
$7.3M
NIDDK NIH HHS T32 DK062707
6 · The paper itself

Abstract

backgroundDiabetic retinopathy (DR) is a serious complication that can progress to sight-threatening disease. The prevalence of DR in youth with diabetes has been reported to be 3.8% to 20%.

objectiveWe aimed to evaluate the prevalence of DR among youth with diabetes at a large ophthalmologic referral center. Secondary goals were to determine the risk factors for DR and severity of disease.

methodsRetrospective chart review of 343 patients with diabetes, <21 years of age, seen at a tertiary referral eye care center from 2013 to 2018.

resultsThe study included 343 patients, of which 293 had type 1 diabetes (T1D) and 50 had type 2 diabetes (T2D). Thirteen of 343 patients had DR, with an overall incidence of 3.8% (3.4% in T1D and 6% T2D). DR severity included nine with mild non-proliferative, three moderate non-proliferative, and one with proliferative DR. Patients with hemoglobin A1c (HbA1c) > 8% had a higher risk of DR (P = .049). In this cohort, none of the patients with an HbA1c <8% had DR. In the multivariate analysis, a higher systolic blood pressure was marginally associated with risk for DR (P = .07).

conclusionsWe found lower prevalence of DR in youth with diabetes than previously reported. The incidence of DR was higher among patients with T2D and occurred with a shorter duration of disease, as compared with T1D. While the incidence of DR in youth with T1D is low, with the increasing incidence of T2D in adolescents and early risk for DR, early screening must be emphasized.

Indexed as

AdolescentAdultAge of OnsetChildDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic RetinopathyHospitals, UrbanHumansOphthalmologyPrevalenceRetrospective StudiesRisk FactorsTertiary Care CentersUnited StatesYoung Adultdiabetes complicationsdiabetic retinopathypediatric diabetesretinopathy screeningrisk factors

Identifiers

PMID32410329
PMCPMC8248280
OpenAlexW3025842120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.