Evidence map›Paper›PMID 32410207›Full record

ArticleInternational journal of clinical pharmacy2020

Effect of a prospective audit with intervention and feedback on Clostridioides difficile infection management.

H Benoist, A de La Blanchardière, A Flatres, C Isnard, P Thibon, G Saint-Lorant

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of clinical pharmacy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Impact of an Intervention Program onOpen forum infectious diseases · 2024
    Article
  2. Article
  3. Article
  4. Improving care for patients withFrontiers in medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

H BenoistDepartment of Pharmacy, Normandie Univ, UNICAEN, CHU de Caen Normandie, Avenue Côte de Nacre, 14000, Caen, France. hubertbenoist@gmail.com.ORCID http://orcid.org/0000-0003-1295-2191
A de La BlanchardièreDepartement of Infectious Diseases, Normandie Univ, UNICAEN, CHU de Caen Normandie, 14000, Caen, France.
A FlatresDepartment of Pharmacy, Normandie Univ, UNICAEN, CHU de Caen Normandie, Avenue Côte de Nacre, 14000, Caen, France.
C IsnardDepartment of Microbiology, Normandie University, UNICAEN, CHU de Caen Normandie, 14000, Caen, France.
P ThibonCPias Normandie, Normandie University, UNICAEN, CHU de Caen Normandie, 14000, Caen, France.
G Saint-LorantDepartment of Pharmacy, Normandie Univ, UNICAEN, CHU de Caen Normandie, Avenue Côte de Nacre, 14000, Caen, France.
Normandie Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Clostridioides difficile infections are associated with morbidity and mortality in several countries. Their increasing incidence and frequent recurrence make them an urgent public health threat. The lack of adherence to international treatment guidelines for Clostridioides difficile infections is a proven mortality risk factor. Objective To evaluate long-term prescribers' adherence to recommendations on the management of Clostridioides difficile infections and its impact on clinical outcomes after an educational and Clostridioides difficile-prospective audit with intervention and feedback period. Setting All patients admitted to a 1500-bed university hospital with positive Clostridioides difficile tests identified were included. Methods Data were collected retrospectively over a baseline period (May-November 2014) and prospectively over a Clostridioides difficile-prospective audit with intervention and feedback period (November 2015-May 2016) and an observation period (November 2017-September 2018). All Clostridioides difficile cases were reviewed by a Clostridioides difficile-prospective audit with intervention and feedback team composed of pharmacists, an infectious diseases specialist and a microbiologist to obtain a complete overview of patient records in each area of expertise. Main outcome measures Percentage of conformity to the protocol, percentage of recovery at 10 days and percentage of relapse, as well as Clostridioides difficile incidence and percentage of Fidaxomicin use. Results A total of 183 patients were included over the three periods. A significant improvement in conformity to the local protocol was observed between the intervention period (23.9%) and the observation period (67.3%) (P < 10

Indexed as

AgedAged, 80 and overAge FactorsAnti-Bacterial AgentsBacteriological TechniquesClinical AuditClinical ProtocolsClostridium InfectionsComorbidityFemaleFidaxomicinFormative FeedbackHumansMaleMiddle AgedPharmacistsAnti-Bacterial AgentsFidaxomicinProton Pump InhibitorsAntimicobial stewardshipAntimicrobial managementClostridium difficileFrance

Identifiers

PMID32410207
OpenAlexW3025116777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.