Evidence map›Paper›PMID 32410180›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2021

Does Chemotherapy-Induced Liver Injury Impair Postoperative Outcomes After Laparoscopic Liver Resection for Colorectal Metastases?

Maud Neuberg, Ioannis Triantafyllidis, Marine Lefevre, Mostefa Bennamoun, Anthony Sarran, Marc Beaussier, Christophe Louvet, Brice Gayet, David Fuks

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Maud NeubergDepartment of Digestive Oncologic and Metabolic Surgery, Institut Mutualiste Montsouris, Université Paris Descartes, 42 boulevard Jourdan, 75014, Paris, France.
Ioannis TriantafyllidisDepartment of Digestive Oncologic and Metabolic Surgery, Institut Mutualiste Montsouris, Université Paris Descartes, 42 boulevard Jourdan, 75014, Paris, France.
Marine LefevreDepartment of Pathology, Institut Mutualiste Montsouris, 42 boulevard Jourdan, 75014, Paris, France.
Mostefa BennamounDepartment of Oncology, Institut Mutualiste Montsouris, 42 boulevard Jourdan, 75014, Paris, France.
Anthony SarranDepartment of Radiology, Institut Mutualiste Montsouris, 42 boulevard Jourdan, 75014, Paris, France.
Marc BeaussierDepartment of Digestive Oncologic and Metabolic Surgery, Institut Mutualiste Montsouris, Université Paris Descartes, 42 boulevard Jourdan, 75014, Paris, France.
Christophe LouvetDepartment of Oncology, Institut Mutualiste Montsouris, 42 boulevard Jourdan, 75014, Paris, France.
Brice GayetDepartment of Digestive Oncologic and Metabolic Surgery, Institut Mutualiste Montsouris, Université Paris Descartes, 42 boulevard Jourdan, 75014, Paris, France.
David FuksDepartment of Digestive Oncologic and Metabolic Surgery, Institut Mutualiste Montsouris, Université Paris Descartes, 42 boulevard Jourdan, 75014, Paris, France. david.fuks@imm.fr.ORCID 0000-0002-4277-7155
Université Paris Cité · FRInstitute Mutualiste Montsouris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChemotherapy-associated liver injuries (CALI) have been associated with poor postoperative outcome after open liver resection. To date, no data concerning any correlation of CALI and laparoscopic liver resection (LLR) are available. In the present study, we evaluated the impact of CALI on short-term outcomes in patients undergoing LLR. MATERIALS AND

methodsAll patients who underwent in our department LLR for colorectal liver metastases (CRLM) from 2000 to 2016 were retrospectively reviewed. Patients were divided in 4 groups according to their pathological histology. In group 1 patients had normal liver parenchyma. Group 2 included patients with steatosis and steatohepatitis. Patients with sinusoidal obstruction syndrome (SOS) and nodular regenerative hyperplasia (NRH) were allocated to group 3, whereas the remaining with fibrosis and cirrhosis, were assigned to group 4.

resultsA total of 490 LLR for CRLM were included in the study. Perioperative details and morbidity did not differ significantly between the four groups. Subgroup analysis showed that NRH was associated with higher amount of blood loss (p = 0.043), overall (p = 0.021) and liver-specific morbidity (p = 0.039).

conclusionNRH is a severe form of CALI that may worsen the short-term outcomes of patients undergoing LLR for CRLM. However, the remaining forms of CALI do not have a significant impact on perioperative outcomes after LLR.

Indexed as

Antineoplastic AgentsColorectal NeoplasmsLaparoscopyLiver NeoplasmsHepatectomyHumansLiverRetrospective StudiesAntineoplastic AgentsCALIChemotherapyColorectal liver metastasesLaparoscopic liver resectionPostoperative outcomes

Identifiers

PMID32410180
OpenAlexW3025091746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.