Evidence map›Paper›PMID 32410178›Full record

SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2020

Current Advances in Minimally Invasive Surgical Management of Perihilar Cholangiocarcinoma.

Amir A Rahnemai-Azar, Arezou Abbasi, Diamantis I Tsilimigras, Sharon M Weber, Timothy M Pawlik

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Changing concepts in perihilar cholangiocarcinoma resections and surgery.International journal of surgery (London, England) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Approach to Resectable Biliary Cancers.Current treatment options in oncology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Amir A Rahnemai-AzarDivision of Surgical Oncology, Department of Surgery, University of Wisconsin School of Medicine, Madison, WI, USA.
Arezou AbbasiDivision of Surgical Oncology, Department of Surgery, University of Washington School of Medicine, Seattle, WA, USA.
Diamantis I TsilimigrasDivision of Surgical Oncology, Department of Surgery, The Ohio State University College of Medicine, Columbus, OH, USA.
Sharon M WeberDivision of Surgical Oncology, Department of Surgery, University of Wisconsin School of Medicine, Madison, WI, USA.
Timothy M PawlikDivision of Surgical Oncology, Department of Surgery, The Ohio State University College of Medicine, Columbus, OH, USA. tim.pawlik@osumc.edu.ORCID http://orcid.org/0000-0002-4828-8096
University of Wisconsin–Madison · USThe Ohio State University · USThe Ohio State University Wexner Medical Center · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile the safety of minimally invasive surgery (MIS) has been reported for several liver malignancies, the role of MIS in the management of perihilar cholangiocarcinoma (pCCA) has been poorly defined.

methodsA systematic review of the literature was performed utilizing MEDLINE/PubMed and Web of Science databases up to January 2020 to assess the safety and feasibility of MIS in the management of patients with pCCA.

resultsLimited data exist on the MIS approach to treat pCCA. Staging laparoscopy carries a low diagnostic yield and typically is used only in select patients with high suspicion of metastatic disease. Data on the use of MIS approach for resection of pCCA have largely been limited to case reports or small case series. A MIS approach to pCCA resection has been demonstrated to be feasible and safe, yet in most series the surgeon failed to include resection of the caudate lobe. Given that caudate lobe involvement occurs in 31-98% of patients with pCCA, incomplete resection of the caudate lobe may be associated with higher local recurrence. More recently, several surgeons have reported complete R0 surgical with removal of the caudate lobe using a MIS approach. While patients may have a shorter length-of-stay, the true benefit of the MIS approach for pCCA needs to be better defined.

conclusionsMIS may be a safe and feasible approach at high-volume centers with robust expertise in the management of patients with pCCA. Further studies with larger number of patients are required prior to universal application of MIS for pCCA.

Indexed as

Bile Duct NeoplasmsCholangiocarcinomaKlatskin TumorLaparoscopyHumansMinimally Invasive Surgical ProceduresNeoplasm Recurrence, LocalBiliary duct malignancyCholangiocarcinomaHilarKlatskin tumorLaparoscopy surgeryMinimally invasive surgeryPerihilar

Identifiers

PMID32410178
OpenAlexW3025362534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.