Evidence map›Paper›PMID 32410174›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2020

Long-Term Surgical Complications After Pancreatoduodenectomy: Incidence, Outcomes, and Risk Factors.

James A Brown, Mazen S Zenati, Richard L Simmons, Amr I Al Abbas, Asmita Chopra, Katelyn Smith, Kenneth K W Lee, Melissa E Hogg, Herbert J Zeh, Alessandro Paniccia and 1 more

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In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Do Complications After Pancreatoduodenectomy Have an Impact on Long-Term Quality of Life and Functional Outcomes?Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
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  17. Incisional hernia repair following pancreatic surgery-open vs laparoscopic approach.Hernia : the journal of hernias and abdominal wall surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

James A BrownSchool of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Mazen S ZenatiDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Richard L SimmonsDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Amr I Al AbbasDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Asmita ChopraDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Katelyn SmithDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Kenneth K W LeeDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Melissa E HoggDepartment of Surgery, Northshore University Health System, Evanston, IL, USA.
Herbert J ZehDepartment of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Alessandro PanicciaDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Amer H ZureikatDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. zureikatah@upmc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term complications following pancreatoduodenectomy (PD) can significantly impact quality of life and healthcare utilization. Most reports focus on short-term (within 90 days) PD outcomes; however, the incidence and risk factors for long-term complications (> 90 days) remain to be evaluated. We sought to identify the incidence, outcomes, and risk factors for long-term complications post-PD.

methodsAll PD survivors between 2010 and 2017 were identified from a single-institutional database. Long-term complications (> 90 days post-PD and not resulting from cancer recurrence), including biliary stricture, cholangitis, pancreatitis, peptic ulcer, small bowel obstruction, and incisional hernia, were identified. Logistic regression was used to identify perioperative predictors of long-term complications.

resultsOf 906 PDs, 628 long-term survivors met criteria for analysis (mean age of 65.3 years, 47% female). Median follow-up and overall survival were 51.1 months (95% CI 47.6, 55.7) and 68.5 months (95% CI 57.9, 81.4), respectively. A total of 198 (31.5%) experienced at least one long-term complication. Complications included incisional hernia (17.7%), biliary stricture or cholangitis (8.0%), pancreatitis (5.7%), small bowel obstruction (4.3%), and peptic ulcer (3.2%). In total, 108 (17.2%) of the complications required an intervention, nearly half of which were surgical. On multivariable analysis, several predictors of long-term complications were identified: obesity (BMI ≥ 30 kg/m

conclusionLong-term complications occur in nearly a third of PDs and nearly one-fifth of all PDs require re-intervention. Several modifiable predictors of long-term complications were identified.

Indexed as

Incisional HerniaPancreaticoduodenectomyAgedFemaleHumansIncidenceMalePostoperative ComplicationsQuality of LifeRetrospective StudiesRisk FactorsLong-term complicationsPancreatoduodenectomyWhipple

Identifiers

PMID32410174

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.