Evidence map›Paper›PMID 32410138›Full record

ArticleMolecular biology reports2020

5-Azacytidine upregulates melatonin MT

Emily E Hartung, Sumeya Z Mukhtar, Syeda M Shah, Lennard P Niles

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Melatonin: A Potential Regulator of DNA Methylation.Antioxidants (Basel, Switzerland) · 2023
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emily E HartungDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Sumeya Z MukhtarDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Syeda M ShahDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Lennard P NilesDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada. niles@mcmaster.ca.ORCID http://orcid.org/0000-0003-1362-1319
McMaster University · CA

Funding

Natural Sciences and Engineering Research Council of Canada. RGPIN-2016-05697
6 · The paper itself

Abstract

The multiple physiological effects of the indoleamine melatonin, are mediated primarily by its two G protein-coupled MT

Indexed as

AnimalsAzacitidineCell LineCell Line, TumorEpigenesis, GeneticGene ExpressionGene Expression Regulation, NeoplasticGliomaHistone Deacetylase InhibitorsHydroxamic AcidsMelatoninRatsReceptor, Melatonin, MT1Receptors, MelatoninRNA, MessengerTranscriptional ActivationAzacitidineHistone Deacetylase InhibitorsHydroxamic AcidsMelatoninReceptor, Melatonin, MT1Receptors, MelatoninRNA, Messengertrichostatin AValproic AcidDNA methylationEpigenetic regulationHistone acetylationMelatonin receptors

Identifiers

PMID32410138
OpenAlexW3025571304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.