ArticleSurgical endoscopy2021
Clinical adhesion score (CLAS): development of a novel clinical score for adhesion-related complications in abdominal and pelvic surgery.
Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Plasma fibrinogen: A novel biomarker for preoperative prediction and quantification of peritoneal adhesions in emergency abdominal surgery.Surgery in practice and science · 2026Article
- Prevention of adhesive small bowel obstruction by anti-adhesion barriers: do they really work?Techniques in coloproctology · 2026Review
- Rats develop more robust and persistent peritoneal adhesion phenotypes than mice: a multimodal comparative study.Scientific reports · 2026Article
- Cellular and molecular regulation of fibrotic postoperative abdominal adhesions.American journal of physiology. Cell physiology · 2026Review
- Chronic kidney disease status and intraoperative adverse events during partial nephrectomy: a propensity-score matched study.Translational andrology and urology · 2026Article
- Preventive role of CD163-positive macrophages in postoperative peritoneal adhesions.Inflammation and regeneration · 2025Article
- A Dual-Layer Hydrogel Barrier Integrating Bio-Adhesive and Anti-Adhesive Properties Prevents Postoperative Abdominal Adhesions.Advanced healthcare materials · 2025Article
- A Scoping Review of Animal Models for Development of Abdominal Adhesion Prevention Strategies.The Journal of surgical research · 2024Article
- Global recommendations on adhesion prophylaxis in gynaecological laparoscopic surgery.Facts, views & vision in ObGyn · 2024Article
- Prevention of post-operative adhesions: Model development and pilot outcomes of human placental stem cell-based interventions.Transfusion · 2024Article
- Perspectives in adhesion prevention in gynaecological surgery.Facts, views & vision in ObGyn · 2023Article
- Appraisal of Intraoperative Adverse Events to Improve Postoperative Care.Journal of clinical medicine · 2023Article
- Safety, efficacy, and operability of a newly developed absorbable adhesion barrier (GM142) in patients with primary rectal cancer scheduled for diverting ileostomy during laparoscopic surgery: Randomized controlled trial.Annals of gastroenterological surgery · 2022Article
- The Future of Adhesion Prophylaxis Trials in Abdominal Surgery: An Expert Global Consensus.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdhesions are a major cause of long-term postsurgical complications in abdominal and pelvic surgery. Existing adhesion scores primarily measure morphological characteristics of adhesions that do not necessarily correlate with morbidity. The aim of this study was to develop a clinical adhesion score (CLAS) measuring overall clinical morbidity of adhesion-related complications in abdominal and pelvic surgery.
methodsAn international Delphi study was performed to identify relevant score items for adhesion-related complications, including small bowel obstruction, female infertility, chronic abdominal or pelvic pain, and difficulties at reoperation. The CLAS includes clinical outcomes, related to morbidity of adhesions, and weight factors, to correct the outcome scores for the likelihood that symptoms are truly caused by adhesions. In a pilot study, two independent researchers retrospectively scored the CLAS in 51 patients to evaluate inter-observer reliability, by calculating the Intraclass correlation coefficient. During a feasibility assessment, we evaluated whether the CLAS completely covered different clinical scenarios of adhesion-related morbidity.
resultsThree Delphi rounds were performed. 43 experts agreed to participate, 38(88%) completed the first round, and 32 (74%) the third round. Consensus was reached on 83.4% of items. Inter-observer reliability for the CLAS was 0.95 (95% CI 0.91-0.97). During feasibility assessment, six items were included. As a result, the CLAS includes 22 outcomes and 23 weight factors.
conclusionThe CLAS represents a promising scoring system to measure and monitor the clinical morbidity of adhesion-related complications. Further studies are needed to confirm its utility in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.