Evidence map›Paper›PMID 32410043›Full record

ArticleNeurochemical research2020

Safflower Yellow Improves the Synaptic Structural Plasticity by Ameliorating the Disorder of Glutamate Circulation in Aβ

Jiawei Hou, Chunhui Wang, Mengyu Zhang, Mengqiao Ren, Guang Yang, Zuwei Qu, Yanli Hu

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Frontiers in pharmacology · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Structural Plasticity of the Hippocampus in Neurodegenerative Diseases.International journal of molecular sciences · 2022
    Review
  10. Hydroxysafflor Yellow A Inhibits AβNeurochemical research · 2022
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jiawei HouKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, People's Republic of China.
Chunhui WangKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, People's Republic of China.
Mengyu ZhangKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, People's Republic of China.
Mengqiao RenKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, People's Republic of China.
Guang YangKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, People's Republic of China.
Zuwei QuKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, People's Republic of China.
Yanli HuKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Department of Pharmacology, Shihezi University, Shihezi, Xinjiang, 832000, People's Republic of China. wzx330@163.com.ORCID http://orcid.org/0000-0002-9811-5572
Shihezi University · CN

Funding

National Natural Science Foundation of China 81660603National Natural Science Foundation of China 81960665
6 · The paper itself

Abstract

Safflower yellow (SY) is the main effective component of Carthamus tinctorius L., and Hydroxysafflor yellow A (HSYA) is the single active component with the highest content in SY. SY and HSYA have been shown to have neuroprotective effects in several AD models. In this study, we aimed to clarify whether the effects of SY and HSYA on the learning and memory abilities of Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsCerebral CortexChalconeDendritic SpinesFemaleGlutamic AcidHippocampusLearningMaleMemoryNeuronal PlasticityNeuroprotective AgentsNootropic AgentsPeptide FragmentsAmyloid beta-Peptidesamyloid beta-protein (1-42)ChalconeGlutamic Acidhydroxysafflor yellow ANeuroprotective AgentsNootropic AgentsPeptide FragmentsQuinonessafflower yellowAlzheimer's diseaseHydroxysafflor yellow ASafflower yellowSynaptic structural plasticity

Identifiers

PMID32410043
OpenAlexW3024642063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.