ArticleMethods in molecular biology (Clifton, N.J.)2020
Analysis of Drosophila melanogaster Lifespan.
Article in Methods in molecular biology (Clifton, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Analysis of Fall and Jump Behaviors in Freely MovingInsects · 2026Article
- Suppression rather than activation of the integrated stress response (GCN2-ATF4) pathway extends lifespan in the fly.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Reproduction and preference to macronutrients have different relations to biological or chronological age in Drosophila.Biogerontology · 2025Article
- De novo variants in CDKL1 and CDKL2 are associated with neurodevelopmental symptoms.American journal of human genetics · 2025Article
- Article
- Deficiency of Gut-Enriched Lipase H Promotes Gut Aging and Reduces Lifespan inPhenomics (Cham, Switzerland) · 2024Article
- Conditional Inhibition of Eip75B Eliminates the Effects of Mating and Mifepristone on Lifespan in FemaleCells · 2024Article
- Response to comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish,eLife · 2023Article
- Studying the Geroprotective Properties of YAP/TAZ Signaling Inhibitors onInternational journal of molecular sciences · 2023Article
- Article
- Increased Iron Levels and Oxidative Stress Mediate Age-Related Impairments in Male and FemaleOxidative medicine and cellular longevity · 2023Article
- Article
- Article
- Lifespan and ROS levels in different Drosophila melanogaster strains after 24 h hypoxia exposure.Biology open · 2022Article
- Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions.Communications biology · 2022Article
- Mifepristone Increases Life Span in FemaleFrontiers in aging · 2022Article
- JNK Signaling inInternational journal of molecular sciences · 2021Review
- Geroprotective potential of genetic and pharmacological interventions to endogenous hydrogen sulfide synthesis in Drosophila melanogaster.Biogerontology · 2021Article
- Metabolic Signatures of Life Span Regulated by Mating, Sex Peptide, and Mifepristone/RU486 in Female Drosophila melanogaster.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- Mifepristone Increases Life Span of Virgin FemaleFrontiers in genetics · 2021Article
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3 authors.
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Abstract
The laboratory fruit fly Drosophila melanogaster is one of the leading models for the study of aging. Whereas several behavioral and physiological biomarkers of aging have been identified for Drosophila, lifespan remains the most robust measure of aging rate. Aging and lifespan can be modulated by genetic alterations, as well as by drugs and dietary components, to reveal basic and conserved mechanisms of aging. Here methods are presented for Drosophila lifespan assay, including media preparation, supplementation of media with various drugs, culturing of the flies, passaging flies and recording deaths, and the analysis of lifespan data.
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