ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2020
Impact of the angle between aortic and mitral annulus on the occurrence of hemolysis during Impella support.
Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Haemolytic injury and cardiovascular disease.Nature reviews. Cardiology · 2026Review
- Echocardiographic Assessment Before, During, and After Impella Positioning: State of the Art.Journal of clinical medicine · 2026Review
- Echocardiography for short-term mechanical circulatory support: a trans-Atlantic practical guide.European heart journal. Imaging methods and practice · 2025Review
- Review
- Monitoring MCS patients on the intensive care unit: integrating haemodynamic assessment, laboratory data, and imaging techniques for timely detection of deterioration and recovery.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Three-year experience of catheter-based micro-axial left ventricular assist device, Impella, in Japanese patients: the first interim analysis of Japan registry for percutaneous ventricular assist device (J-PVAD).Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2023Article
- Echocardiographic imaging of temporary percutaneous mechanical circulatory support devices.Journal of echocardiography · 2022Review
- Prognostic implication of risk scoring systems in patients with cardiogenic shock supported by ECMO and Impella.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite optimal management, we sometimes experience refractory hemolysis requiring extensive device speed reduction or continuous hemodiafiltration following Impella implantation. However, pre-procedural predictors of such a refractory hemolysis remain unknown. In this study, we investigated the pre-procedural factors, including the echocardiographic narrow angle between aortic and mitral annulus, associating with the occurrence of refractory hemolysis following Impella insertion. We enrolled 26 patients (71 years, 65% male) who received Impella insertion between March 2018 and November 2019. Among baseline characteristics, the angle between aortic and mitral annulus, < 126.5°, was an independent risk factor of refractory hemolysis with an adjusted hazard ratio of 7.840 (95% confidence interval 0.925-66.44) and was associated with lower 30-day survival (64% vs. 100%, p = 0.0116). The narrow angle between aortic and mitral annulus might be a useful tool to risk-stratify the occurrence of refractory hemolysis following Impella insertion.
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Registered trials
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