Evidence map›Paper›PMID 32409990›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Impact of cardiovascular comorbidities on inpatient mortality in patients hospitalized with neutropenic fever.

Suheil Albert Atallah-Yunes, Anis John Kadado, Faris Haddadin, Khalid Sawalha, Jaime Hernandez-Montfort, Syed S Ali

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cardiovascular Toxicity of BTKi in Chronic B-Cell Malignancies.Reviews in cardiovascular medicine · 2026
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suheil Albert Atallah-YunesDepartment of Medicine, University of Massachusetts Medical School, Baystate Medical Center, 759 Chestnut St., Springfield, MA, 01199, USA.
Anis John KadadoDepartment of Medicine, University of Massachusetts Medical School, Baystate Medical Center, 759 Chestnut St., Springfield, MA, 01199, USA.
Faris HaddadinDepartment of Medicine, Mount Sinai St Luke's and West, New York, NY, 1090, USA.
Khalid SawalhaDepartment of Medicine, University of Massachusetts Medical School, Baystate Medical Center, 759 Chestnut St., Springfield, MA, 01199, USA. khalid.sawalhamd@baystatehealth.org.
Jaime Hernandez-MontfortHeart and vascular institute, Cleveland Clinic Florida, Weston, FL, 33331, USA.
Syed S AliDepartment of Hematology/Oncology, Saint Francis Cancer Center, Hartford, CT, 06105, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionConcomitant cardiovascular comorbidities in patients with cancer are not uncommon. There is limited data on the impact of cardiovascular comorbidities on in-hospital mortality in patients admitted with neutropenic fever.

methodsThis is a retrospective cohort study using the 2016 NIS database of adults (> 18 years old) hospitalized for neutropenic fever as the primary diagnosis. The primary outcome studied is all-cause mortality in patients with neutropenic fever. ICD-10-CM codes were used to identify cardiovascular risk factors including smoking; hyperlipidemia; peripheral vascular diseases; hypertension; history of cerebrovascular disease or transient ischemic attack; and cardiovascular morbidities including atrial fibrillation, coronary artery disease, and congestive heart failure. Multivariate linear regression analysis was used to adjust for cofounders.

resultsA total of 28,060 patients were admitted with neutropenic fever in 2016. Average age was 43.9 ± 1.7 years, and 49.3% were females. Among the cases identified, 205 patients died during hospitalization with an overall in-hospital mortality of 0.7%. Atrial fibrillation was independently associated with higher in-hospital mortality (odds ratio [OR] 3.01; CI 1.38 to 6.57; p = 0.005) as was congestive heart failure (OR 3.15; CI 1.08 to 10.14; p = 0.049).

conclusionAtrial fibrillation and congestive heart failure were associated with higher inpatient mortality in patients with neutropenic fever. Identifying the risk factors for increased mortality in patients with neutropenic fever is important for risk stratification and guiding clinicians in taking therapeutic decisions in this set of patients.

Indexed as

AdultCardiovascular DiseasesCohort StudiesComorbidityFebrile NeutropeniaFemaleHospitalizationHospital MortalityHumansInpatientsMaleRetrospective StudiesAtrial fibrillationCancerHeart failureNeutropenic fever

Identifiers

PMID32409990

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