Evidence map›Paper›PMID 32409977›Full record

ArticleThe international journal of cardiovascular imaging2020

Angiography-derived index of microcirculatory resistance as a novel, pressure-wire-free tool to assess coronary microcirculation in ST elevation myocardial infarction.

Giovanni Luigi De Maria, Roberto Scarsini, Mayooran Shanmuganathan, Rafail A Kotronias, Dimitrios Terentes-Printzios, Alessandra Borlotti, Jeremy P Langrish, Andrew J Lucking, Robin P Choudhury, Rajesh Kharbanda and 5 more

2 registry-linked trialsOpen access · hybridAbstract readComparative StudyValidation Study
In one paragraph

Article in The international journal of cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 77 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 4 pooled it
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04825028 unknown statusnot on this mapstarted 2021, after this paper: background citation

Diagnostic Value of Angiography-derived Index of Microvascular Resistance in Coronary Artery Disease Patients and Its Prognostic Implication After Percutaneous Coronary Intervention

TypeobservationalSponsorShanghai Zhongshan HospitalRan2021 to 2021Enrolled271ConditionsCoronary Microvascular Dysfunction, Myocardial IschemiaArmsAngiography-drived Index of Microcirculatory Resistance
NCT05760157 unknown statusnot on this mapstarted 2023, after this paper: background citation

To Establish a Multimodal Dynamic Risk Assessment System of Heart Failure in Patients With Myocardial Infarction Based on Coronary Microcirculation.

TypeobservationalSponsorJian LiuRan2023 to 2025Enrolled567ConditionsHeart Failure, Acute Myocardial InfarctionArmsPossible risk factors of heart failure
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 4 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
  2. Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Observational
  8. Coronary microvascular dysfunction: a narrative review.Cardiovascular diagnosis and therapy · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Vascular (dys)function in the failing heart.Nature reviews. Cardiology · 2025
    Review
  17. Prognostic impact of angiography-derived index of microcirculatory resistance in patients with dilated cardiomyopathy.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
  18. Single-view angiographic microcirculatory resistance index after primary PCI: the EARLY-MYO-AMR study.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  19. Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Giovanni Luigi De MariaOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Roberto ScarsiniOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Mayooran ShanmuganathanOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Rafail A KotroniasOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Dimitrios Terentes-PrintziosOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Alessandra BorlottiOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Jeremy P LangrishOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Andrew J LuckingOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Robin P ChoudhuryOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Rajesh KharbandaOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Vanessa M FerreiraOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Oxford Acute Myocardial Infarction (OXAMI) Study Investigators
Keith M ChannonOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK.
Hector M Garcia-GarciaMedStar Washington Hospital Center, Washington, DC, USA.
Adrian P BanningOxford Heart Centre, NIHR Biomedical Research Centre, Oxford University Hospitals, Headley Way, Oxford, OX39DU, UK. adrian.banning@ouh.nhs.uk.
University of Oxford · GBMedStar Washington Hospital Center · USOxford BioMedica (United Kingdom) · GB

Funding

BHF Centre of Research Excellence, Oxford (GB) RG/13/1/30181British Heart Foundation CH/16/1/32013
6 · The paper itself

Abstract

Immediate assessment of coronary microcirculation during treatment of ST elevation myocardial infarction (STEMI) may facilitate patient stratification for targeted treatment algorithms. Use of pressure-wire to measure the index of microcirculatory resistance (IMR) is possible but has inevitable practical restrictions. We aimed to develop and validate angiography-derived index of microcirculatory resistance (IMR

Indexed as

Coronary AngiographyCoronary CirculationMicrocirculationVascular ResistanceAgedAngioplasty, Balloon, CoronaryBlood Flow VelocityCardiac CatheterizationCardiac CathetersCoronary Artery DiseaseCoronary VesselsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedIndex of microcirculatory resistanceMicrovascular dysfunctionMicrovascular obstructionQuantitative flow ratioSTEMI

Identifiers

PMID32409977
PMCPMC7381481
OpenAlexW3024765166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.