Evidence map›Paper›PMID 32409927›Full record

SynthesisArchives of gynecology and obstetrics2020

A high Glasgow prognostic score (GPS) or modified Glasgow prognostic score (mGPS) predicts poor prognosis in gynecologic cancers: a systematic review and meta-analysis.

Dan Nie, Lingping Zhang, Chunyan Wang, Qian Guo, Xiguang Mao

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of gynecology and obstetrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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  5. Predicting intestinal ischemia in mechanical intestinal obstruction: the role of the C-reactive protein-albumin-lymphocyte index.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dan NieDepartment of Gynecology, Affiliated Hospital of Southwest Medical University, No.8 Section 2, Kangcheng Road, Luzhou, Sichuan, 646000, People's Republic of China. niedan@swmu.edu.cn.ORCID http://orcid.org/0000-0003-0750-6445
Lingping ZhangFirst Department of Respiratory Medicine, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, People's Republic of China.
Chunyan WangDepartment of Gynecology, Affiliated Hospital of Southwest Medical University, No.8 Section 2, Kangcheng Road, Luzhou, Sichuan, 646000, People's Republic of China.
Qian GuoDepartment of Gynecology, Affiliated Hospital of Southwest Medical University, No.8 Section 2, Kangcheng Road, Luzhou, Sichuan, 646000, People's Republic of China.
Xiguang MaoDepartment of Gynecology, Affiliated Hospital of Southwest Medical University, No.8 Section 2, Kangcheng Road, Luzhou, Sichuan, 646000, People's Republic of China.
Affiliated Hospital of Southwest Medical University · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Glasgow Prognostic Score or modified Glasgow Prognostic Score (GPS/mGPS), a novel inflammatory indicator, which acts as a prognostic predictor in various cancers. However, these results are still controversial. In this meta-analysis, we aimed to investigate the prognostic role of GPS/mGPS in patients with gynecologic cancers.

methodsWe explored eligible studies by searching the databases PubMed, the Cochrane Library, EMBASE, and Web of Science. The hazard ratio (HR) and odds ratios (OR) with 95% confidence intervals (CIs) were extracted to investigate the correlation between GPS/mGPS and overall survival (OS) and progression-free survival (PFS). Additionally, we performed subgroup analyses to detect the potential heterogeneity in our study.

results11 studies involving 2830 patients were enrolled in this meta-analysis. The results revealed that a high GPS was significantly related to a shorter OS (pooled HR = 1.94; 95% CI = 1.54-2.43; P < 0.001) and PFS (pooled HR = 1.92; 95% CI = 1.56-2.35; P < 0.001) in patients with gynecologic cancers. Moreover, mGPS also predicted poor OS (pooled HR = 1.67; 95% CI = 1.41-1.96; P < 0.001) and PFS (pooled HR = 1.73; 95% CI = 1.47-2.04; P < 0.001) in gynecologic cancers patients.

conclusionA higher GPS/mGPS is correlated with poor survival outcomes in patients with gynecologic cancers. Pretreatment GPS/mGPS is a valid prognostic predictor in gynecologic cancers.

Indexed as

FemaleGenital Neoplasms, FemaleGlasgow Outcome ScaleHumansPrognosisProgression-Free SurvivalSurvival AnalysisGlasgow prognostic scoreGynecologic cancerModified Glasgow prognostic scorePrognosis

Identifiers

PMID32409927
OpenAlexW3025606072

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.