Evidence map›Paper›PMID 32409778›Full record

ArticleSpinal cord2020

A pragmatic randomized controlled trial testing the effects of the international scientific SCI exercise guidelines on SCI chronic pain: protocol for the EPIC-SCI trial.

Kathleen A Martin Ginis, Jan W van der Scheer, Kendra R Todd, Jennifer C Davis, Sonja Gaudet, Femke Hoekstra, Mohammad Ehsanul Karim, John L K Kramer, Jonathan Peter Little, Joel Singer and 2 more

Erratum issuedOpen access · bronzeAbstract readClinical Trial Protocol
PubMed Publisher
In one paragraph

Article in Spinal cord, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Kathleen A Martin GinisDepartment of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, BC, Canada. kathleen_martin.ginis@ubc.ca.ORCID http://orcid.org/0000-0002-7076-3594
Jan W van der ScheerDepartment of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, BC, Canada.
Kendra R ToddSchool of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.
Jennifer C DavisCentre for Chronic Disease Prevention and Management, University of British Columbia, Kelowna, BC, Canada.
Sonja GaudetSpinal Cord Injury British Columbia, Vancouver, BC, Canada.
Femke HoekstraSchool of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.ORCID http://orcid.org/0000-0002-0068-652X
Mohammad Ehsanul KarimSchool of Population and Public Health and Centre for Health Evaluation and Outcome Sciences, Providence Health Care, University of British Columbia, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0002-0346-2871
John L K KramerInternational Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, BC, Canada.
Jonathan Peter LittleSchool of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.
Joel SingerSchool of Population and Public Health, UBC; Centre for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada.
Andrea TownsonDepartment of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, BC, Canada.
Christopher R WestInternational Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, BC, Canada.
University of British Columbia · CACentre for Advancing Health Outcomes · CAInterior Health · CAProvidence Health Care · CASpinal Cord Injury BC · CA

Funding

Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) #PJT-165903
6 · The paper itself

Abstract

STUDY

designProtocol for a pragmatic randomized controlled trial (the Exercise guideline Promotion and Implementation in Chronic SCI [EPIC-SCI] Trial). PRIMARY

objectivesTo test if home-/community-based exercise, prescribed according to the international SCI exercise guidelines, significantly reduces chronic bodily pain in adults with SCI. SECONDARY

objectivesTo investigate: (1) the effects of exercise on musculoskeletal and neuropathic chronic pain; (2) if reduced inflammation and increased descending inhibitory control are viable pathways by which exercise reduces pain; (3) the effects of chronic pain reductions on subjective well-being; and (4) efficiency of a home-/community-based exercise intervention.

settingExercise in home-/community-based settings; assessments in university-based laboratories in British Columbia, Canada.

methodEighty-four adults with chronic SCI, reporting chronic musculoskeletal or neuropathic pain, and not meeting the current SCI exercise guidelines, will be recruited and randomized to a 6-month Exercise or Wait-List Control condition. Exercise will occur in home/community settings and will be supported through behavioral counseling. All measures will be taken at baseline, 3-months and 6-months. Analyses will consist of linear mixed effect models, multiple regression analyses and a cost-utility analysis. The economic evaluation will examine the incremental costs and health benefits generated by the intervention compared with usual care. ETHICS AND DISSEMINATION: The University of British Columbia Clinical Research Ethics Board approved the protocol (#H19-01650). Using an integrated knowledge translation approach, stakeholders will be engaged throughout the trial and will co-create and disseminate evidence-based recommendations and messages regarding the use of exercise to manage SCI chronic pain.

Indexed as

Chronic PainExercise TherapyMusculoskeletal PainNeuralgiaOutcome Assessment, Health CareSpinal Cord InjuriesAdultCost-Benefit AnalysisFollow-Up StudiesHumansPractice Guidelines as TopicPragmatic Clinical Trials as Topic

Identifiers

PMID32409778
OpenAlexW4206249739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.