Evidence map›Paper›PMID 32409659›Full record

ArticleScientific reports2020

rTgOWP1-f, a specific biomarker for Toxoplasma gondii oocysts.

Susana Sousa, André Almeida, Lurdes Delgado, Antónia Conceição, Cláudia Marques, José Manuel Correia da Costa, António Castro

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Susana SousaCenter for Parasite Biology and Immunology, National Institute of Health Dr Ricardo Jorge, Rua Alexandre Herculano 321, 4000-055, Porto, Portugal. adelaide.sousa@insa.min-saude.pt.
André AlmeidaCenter for the Study of Animal Science (CECA)/Institute for Agricultural and Agro-Alimentary Science and Technology (ICETA), University of Porto, Porto, Portugal.
Lurdes DelgadoCenter for Parasite Biology and Immunology, National Institute of Health Dr Ricardo Jorge, Rua Alexandre Herculano 321, 4000-055, Porto, Portugal.
Antónia ConceiçãoCoimbra Polytechnic PT, Bencanta, 3045-601, Coimbra, Portugal.
Cláudia MarquesCenter for Parasite Biology and Immunology, National Institute of Health Dr Ricardo Jorge, Rua Alexandre Herculano 321, 4000-055, Porto, Portugal.
José Manuel Correia da CostaCenter for Parasite Biology and Immunology, National Institute of Health Dr Ricardo Jorge, Rua Alexandre Herculano 321, 4000-055, Porto, Portugal.
António CastroCenter for Parasite Biology and Immunology, National Institute of Health Dr Ricardo Jorge, Rua Alexandre Herculano 321, 4000-055, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasma gondii oocyst wall protein 1 (TgOWP1) integrates a family of seven proteins, consensually assumed as specific antigens of Toxoplasma gondii oocyst stage, located in the outer layer of the oocyst wall. Herein, we notice the expression of a recombinant antigen, rTgOWP1-f, derived from a fragment selected on basis of its structural homology with Plasmodium MSP1-19. Rabbit polyclonal antibodies anti-rTgOWP1-f evidence ability for specific identification of environmental T. gondii oocysts. We assume, rTgOWP1-f, as a possible biomarker of oocysts. In addition, we present findings supporting this vision, including the development of an immunodetection method for T. gondii oocysts identification.

Indexed as

Amino Acid SequenceBiomarkersModels, MolecularOocystsProtein ConformationProtozoan ProteinsToxoplasmaBiomarkersProtozoan Proteins

Identifiers

PMID32409659
PMCPMC7224171

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.