Evidence map›Paper›PMID 32409630›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2020

A Population-Based Analysis of Distant Metastasis in Stage IV Gastric Cancer.

Yiran Zhang, Yile Lin, Jincai Duan, Ke Xu, Min Mao, Xin Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yiran ZhangInternational Medical Center, Tianjin First Central Hospital, Tianjin, China (mainland).
Yile LinClinical Medical College of Tianjin Medical University, Tianjin, China (mainland).
Jincai DuanClinical Medical College of Tianjin Medical University, Tianjin, China (mainland).
Ke XuClinical Medical College of Tianjin Medical University, Tianjin, China (mainland).
Min MaoDepartment of Pathology and Southwest Cancer Center, First Affiliated Hospital, Army Medical University, Chongqing, China (mainland).
Xin WangDepartment of Epidemiology and Biostatistics, First Affiliated Hospital, Army Medical University, Chongqing, China (mainland).
Tianjin Medical University · CNArmy Medical University · CNSouthwest Hospital · CNTianjin First Center Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Distant metastasis (DM) is a crucial problem in management of patients with gastric cancer. Identification of the risk factors for development of DM and the prognostic factors for patients with DM is essential in development of individualized treatment of patients at the advanced stage with specific metastasis. MATERIAL AND METHODS Records of patients with gastric cancer were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Survival duration of patients with specific DM was estimated, and the prognostic factors were investigated using the Cox proportional hazard regression model. The logistic regression model was used to reveal the inherent risk factors for development of DM. RESULTS Eventually, 32.6% (11,918 out of 36,588) of gastric cancer patients were diagnosed with DM between 2010 and 2015, among whom 5,361, 1,778, 1,495, and 231 patients were diagnosed with liver, lung, bone, and brain metastasis, respectively. The median overall survival for patients with DM was 5.0 (95% CI: 4.8-5.2) months, with a 5-year survival rate of 3.9%. Primary tumor site, histology types, tumor grade, T stage, N stage, surgery, chemotherapy, and the number of metastases were associated with worse survival. Younger age and higher tumor grade were positively associated with the development of DM. CONCLUSIONS Initial DM was found in 32.6% of patients with gastric cancer. Homogenous and heterogenous predictive factors were identified for patients with a specific metastatic site, which can be used in targeted screening and individualized treatment.

Indexed as

Brain NeoplasmsFemaleHumansKaplan-Meier EstimateLiver NeoplasmsLung NeoplasmsMaleNeoplasm MetastasisNeoplasm StagingPrognosisProportional Hazards ModelsRisk FactorsSEER ProgramStomach NeoplasmsSurvival Rate

Identifiers

PMID32409630
PMCPMC7245058
OpenAlexW3028125403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.