Evidence map›Paper›PMID 32409579›Full record

ArticleThe Journal of biological chemistry2020

Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1.

Sophie M Travis, Kevin DAmico, I-Mei Yu, Conor McMahon, Safraz Hamid, Gabriel Ramirez-Arellano, Philip D Jeffrey, Frederick M Hughson

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. GARP Complex in Golgi Physiology.Sub-cellular biochemistry · 2026
    Review
  3. Article
  4. Review
  5. The machinery of vesicle fusion.Current opinion in cell biology · 2023
    Review
  6. Article
  7. Role of GARP Vesicle Tethering Complex in Golgi Physiology.International journal of molecular sciences · 2023
    Review
  8. Review
  9. Review
  10. Article
  11. Chaperoning SNARE Folding and Assembly.Annual review of biochemistry · 2021
    Review
  12. Article
  13. Golgi inCOGnito: From vesicle tethering to human disease.Biochimica et biophysica acta. General subjects · 2020
    Review
  14. Securing SNAREs for assembly.The Journal of biological chemistry · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sophie M TravisDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.ORCID 0000-0002-1728-1705
Kevin DAmicoDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
I-Mei YuDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
Conor McMahonDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
Safraz HamidDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
Gabriel Ramirez-ArellanoDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
Philip D JeffreyDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
Frederick M HughsonDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA hughson@princeton.edu.
Princeton University · US

Funding

X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Sean McSweeney · 2019 to 2026
$38.6M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007388 · NIGMS · PRINCETON UNIVERSITY · PI CRISTEA, ILEANA M. · 1985 to 2022
$27.4M
Life Science and Biomedical technology Research center at NSLS-II LSBRP41GM111244 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI MCSWEENEY, SEAN · 2014 to 2018
$16.4M
Structural Analysis of Membrane Tethering and Fusion ProteinsR01GM071574 · NIGMS · PRINCETON UNIVERSITY · PI HUGHSON, FREDERICK M · 2005 to 2024
$6.8M
NIGMS NIH HHS P30 GM133893NIGMS NIH HHS P41 GM111244NIGMS NIH HHS R01 GM071574NIGMS NIH HHS T32 GM007388
6 · The paper itself

Abstract

Multisubunit-tethering complexes (MTCs) are large (250 to >750 kDa), conserved macromolecular machines that are essential for soluble

Indexed as

Models, MolecularCrystallography, X-RayProtein Structure, QuaternarySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSNARE ProteinsDSL1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSNARE ProteinsCATCHR complexCOPIDsl1 complexmembrane traffickingmultisubunit tethering complexSNARE proteinvesicleX-ray crystallographyyeast

Identifiers

PMID32409579
PMCPMC7383367
OpenAlexW3025031765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.