Evidence map›Paper›PMID 32409328›Full record

SynthesisBMJ global health2020

Safe management of bodies of deceased persons with suspected or confirmed COVID-19: a rapid systematic review.

Sally Yaacoub, Holger J Schünemann, Joanne Khabsa, Amena El-Harakeh, Assem M Khamis, Fatimah Chamseddine, Rayane El Khoury, Zahra Saad, Layal Hneiny, Carlos Cuello Garcia and 17 more

Abstract readSystematic Review
In one paragraph

Synthesis in BMJ global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Rate of shed of SARS COV-2 viral RNA from COVID-19 cadavers.Journal of infection and public health · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Autopsies in pandemics - a perspective on barriers and benefits. Is it time for a revival?APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2021
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Perils of human remains examination in COVID-19 times.Journal of forensic and legal medicine · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Sally YaacoubClinical Research Institute, American University of Beirut, Beirut, Lebanon.ORCID 0000-0003-0819-1561
Holger J SchünemannWHO Collaborating Centre for Infectious Diseases, McMaster University, Hamilton, Ontario, Canada.
Joanne KhabsaClinical Research Institute, American University of Beirut, Beirut, Lebanon.ORCID 0000-0002-4336-3501
Amena El-HarakehClinical Research Institute, American University of Beirut, Beirut, Lebanon.
Assem M KhamisHull York Medical School, University of Hull, Hull, UK.ORCID 0000-0002-5567-7065
Fatimah ChamseddineClinical Research Institute, American University of Beirut, Beirut, Lebanon.
Rayane El KhouryClinical Research Institute, American University of Beirut, Beirut, Lebanon.
Zahra SaadGlobal Evidence Synthesis Initiative, American University of Beirut, Beirut, Lebanon.
Layal HneinyUniversity Libraries, Saab Medical Library, American University of Beirut, Beirut, Lebanon.
Carlos Cuello GarciaDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Giovanna Elsa Ute Muti-SchünemannMedical School, Vita Salute San Raffaele University, Milano, Italy.
Antonio BognanniDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Chen ChenGuangzhou University of Chinese Medicine, The Fourth Clinical Medical College, Guangdong, China.
Guang ChenBeijing University of Chinese Medicine, Dongzhimen Hospital, Beijing, China.
Yuan ZhangDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Hong ZhaoInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China.
Pierre Abi HannaInfectious Disease Division, Rafik Hariri University Hospital, Beirut, Lebanon.
Mark LoebDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Thomas PiggottDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Marge ReinapLondon School of Hygiene and Tropical Medicine, London, UK.
Nesrine RizkDivision of Infectious Diseases, American University of Beirut, Beirut, Lebanon.
Rosa StalteriDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Stephanie DudaDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Karla SoloDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-6134-9140
Derek K ChuDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-8269-4496
Elie A AklClinical Research Institute, American University of Beirut, Beirut, Lebanon ea32@aub.edu.lb.
COVID-19 Systematic Urgent Reviews Group Effort (SURGE) group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionProper strategies to minimise the risk of infection in individuals handling the bodies of deceased persons infected with 2019 novel coronavirus (2019-nCoV) are urgently needed. The objective of this study was to systematically review the literature to scope and assess the effects of specific strategies for the management of the bodies.

methodsWe searched five general, three Chinese and four coronavirus disease (COVID-19)-specific electronic databases. We searched registries of clinical trials, websites of governmental and other relevant organisations, reference lists of the included papers and relevant systematic reviews, and Epistemonikos for relevant systematic reviews. We included guidance documents providing practical advice on the handling of bodies of deceased persons with suspected or confirmed COVID-19. Then, we sought primary evidence of any study design reporting on the efficacy and safety of the identified strategies in coronaviruses. We included evidence relevant to contextual factors (ie, acceptability). A single reviewer extracted data using a pilot-tested form and graded the certainty of the evidence using the GRADE approach. A second reviewer verified the data and assessments.

resultsWe identified one study proposing an uncommon strategy for autopsies for patients with severe acute respiratory syndrome. The study provided very low-certainty evidence that it reduced the risk of transmission. We identified 23 guidance documents providing practical advice on the steps of handling the bodies: preparation, packing, and others and advice related to both the handling of the dead bodies and the use of personal protective equipment by individuals handling them. We did not identify COVID-19 evidence relevant to any of these steps.

conclusionWhile a substantive number of guidance documents propose specific strategies, we identified no study providing direct evidence for the effects of any of those strategies. While this review highlights major research gaps, it allows interested entities to build their own guidance.

Indexed as

CadaverCoronavirusPractice Guidelines as TopicCoronavirus InfectionsCOVID-19HumansMortuary PracticePandemicsPneumonia, Viralprevention strategiespublic healthrespiratory infectionssystematic review

Identifiers

PMID32409328
PMCPMC7234869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.