Evidence map›Paper›PMID 32408651›Full record

ArticleJournal of clinical medicine2020

Can Circulating Cardiac Biomarkers Be Helpful in the Assessment of

Przemyslaw Chmielewski, Ewa Michalak, Ilona Kowalik, Maria Franaszczyk, Malgorzata Sobieszczanska-Malek, Grazyna Truszkowska, Malgorzata Stepien-Wojno, Elzbieta Katarzyna Biernacka, Bogna Foss-Nieradko, Michal Lewandowski and 8 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. The Time Has Come to Explore Plasma Biomarkers in Genetic Cardiomyopathies.International journal of molecular sciences · 2021
    Review
  9. Article
  10. A NovelDiagnostics (Basel, Switzerland) · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Przemyslaw ChmielewskiUnit for Screening Studies in Inherited Cardiovascular Diseases, National Institute of Cardiology, 04-628 Warsaw, Poland.
Ewa MichalakUnit for Screening Studies in Inherited Cardiovascular Diseases, National Institute of Cardiology, 04-628 Warsaw, Poland.
Ilona KowalikDepartment of Coronary Artery Disease and Cardiac Rehabilitation, National Institute of Cardiology, 04-628 Warsaw, Poland.
Maria FranaszczykMolecular Biology Laboratory, Department of Medical Biology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Malgorzata Sobieszczanska-MalekDepartment of Heart Failure and Transplantology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Grazyna TruszkowskaMolecular Biology Laboratory, Department of Medical Biology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Malgorzata Stepien-WojnoUnit for Screening Studies in Inherited Cardiovascular Diseases, National Institute of Cardiology, 04-628 Warsaw, Poland.
Elzbieta Katarzyna BiernackaDepartment of Congenital Heart Diseases, National Institute of Cardiology, 04-628 Warsaw, Poland.
Bogna Foss-NieradkoUnit for Screening Studies in Inherited Cardiovascular Diseases, National Institute of Cardiology, 04-628 Warsaw, Poland.
Michal Lewandowski2nd Department of Arrhythmia, National Institute of Cardiology, 04-628 Warsaw, Poland.
Artur Oreziak1st Department of Arrhythmia, National Institute of Cardiology, 04-628 Warsaw, Poland.
Maria Bilinska1st Department of Arrhythmia, National Institute of Cardiology, 04-628 Warsaw, Poland.
Mariusz KusmierczykDepartment of Cardiac Surgery and Transplantology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Frédérique TessonInterdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Jacek GrzybowskiDepartment of Cardiomyopathy, National Institute of Cardiology, 04-628 Warsaw, Poland.
Tomasz ZielinskiDepartment of Heart Failure and Transplantology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Rafal PloskiDepartment of Medical Genetics, Medical University of Warsaw, 02-106 Warsaw, Poland.
Zofia T BilinskaUnit for Screening Studies in Inherited Cardiovascular Diseases, National Institute of Cardiology, 04-628 Warsaw, Poland.
Institute of Cardiology · PLMedical University of Warsaw · PLUniversity of Ottawa · CA

Funding

Komitet Badań Naukowych 0010/P05B/98/14Narodowe Centrum Badań i Rozwoju ERA-CVD DETECTIN-HF/2/2017Narodowym Centrum Nauki 2011/01/B/NZ4/03455National Institute of Cardiology, Warsaw, Poland 2.10/II/10National Institute of Cardiology, Warsaw, Poland 2.18/II/08National Institute of Cardiology, Warsaw, Poland 2.56/II/14National Institute of Cardiology, Warsaw, Poland 2.57/VII/03
6 · The paper itself

Abstract

Mutations in the lamin A/C gene are variably phenotypically expressed; however, it is unclear whether circulating cardiac biomarkers are helpful in the detection and risk assessment of cardiolaminopathies. We sought to assess (1) clinical characteristics including serum biomarkers: high sensitivity troponin T (hsTnT) and N-terminal prohormone brain natriuretic peptide (NT-proBNP) in clinically stable cardiolaminopathy patients, and (2) outcome among pathogenic/likely pathogenic lamin A/C gene (

Indexed as

arrhythmic risk stratificationbiomarkerslaminopathyLMNAmalignant ventricular arrhythmiaNT-proBNPtroponin T

Identifiers

PMID32408651
PMCPMC7290314
OpenAlexW3025989931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.