Evidence map›Paper›PMID 32408403›Full record

ArticleExperimental neurobiology2020

Intracerebral Transplantation of BDNF-overexpressing Human Neural Stem Cells (HB1.F3.BDNF) Promotes Migration, Differentiation and Functional Recovery in a Rodent Model of Huntington's Disease.

Hyun Sook Kim, Iksoo Jeon, Jeong-Eun Noh, Hyunseung Lee, Kwan Soo Hong, Nayeon Lee, Zhong Pei, Jihwan Song

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Disruption of BDNF signalling in neuropathologies.Biochemical Society transactions · 2026
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  5. Wrap it up: myelination of transplanted neurons for repair.Frontiers in cellular neuroscience · 2025
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  11. Stem Cell Therapy in Treating Epilepsy.Frontiers in neuroscience · 2022
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyun Sook KimDepartment of Neurology, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Iksoo JeonCHA Stem Cell Institute, Department of Biomedical Science, CHA University, Seongnam 13488, Korea.
Jeong-Eun NohCHA Stem Cell Institute, Department of Biomedical Science, CHA University, Seongnam 13488, Korea.
Hyunseung LeeDivision of Magnetic Imaging Resonance, Korea Basic Science Institute, Cheongju 28119, Korea.
Kwan Soo HongDivision of Magnetic Imaging Resonance, Korea Basic Science Institute, Cheongju 28119, Korea.
Nayeon LeeCHA Stem Cell Institute, Department of Biomedical Science, CHA University, Seongnam 13488, Korea.
Zhong PeiDepartment of Neurology, National Key Clinical Department and Key Discipline of Neurology, Th e First Affi liated Hospital of Sun Yat-sen University, Guangzhou 510080, China.
Jihwan SongCHA Stem Cell Institute, Department of Biomedical Science, CHA University, Seongnam 13488, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by abnormally expanded CAG repeats in the

Indexed as

Behavioral recoveryBrain-derived neurotrophic factor (BDNF)Huntington's disease (HD)Magnetic resonance imaging (MRI)Neural stem cells

Identifiers

PMID32408403
PMCPMC7237270

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.