Evidence map›Paper›PMID 32408186›Full record

ArticleClinical biomechanics (Bristol, Avon)2020

Lesser magnitudes of lower extremity variability during terminal swing characterizes walking patterns in children with autism.

Jeffrey D Eggleston, John R Harry, Patrick A Cereceres, Alyssa N Olivas, Emily A Chavez, Jason B Boyle, Janet S Dufek

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05236803 (Better Understand Motor Deficits Associated With Autism Spectrum Disorders), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05236803 narecruitingnot on this mapstarted 2022, after this paper: background citation

Better Understand Motor Deficits Associated With Autism Spectrum Disorders: Development of an Assessment Protocol

TypeinterventionalSponsorCentre Hospitalier Charles Perrens, BordeauxRan2022 to 2027Enrolled110ConditionsAutism Spectrum DisorderArmsTesting of general motor skills, fine motor skills and occulomotricity, Questionnaires
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey D EgglestonDepartment of Kinesiology, University of Texas at El Paso, El Paso, TX, USA. Electronic address: jdeggleston@utep.edu.
John R HarryDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
Patrick A CereceresDepartment of Kinesiology, University of Texas at El Paso, El Paso, TX, USA.
Alyssa N OlivasDepartment of Biomedical Engineering, University of Texas at El Paso, El Paso, TX, USA.
Emily A ChavezDepartment of Kinesiology, University of Texas at El Paso, El Paso, TX, USA.
Jason B BoyleDepartment of Kinesiology, University of Texas at El Paso, El Paso, TX, USA.
Janet S DufekDepartment of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, NV, USA.

Funding

Tracking and EvaluationU54GM104944 · NIGMS · UNIVERSITY OF NEVADA LAS VEGAS · PI ZHU, YILIANG · 2013 to 2023
$39.6M
NIGMS NIH HHS U54 GM104944
6 · The paper itself

Abstract

backgroundAnecdotally, children with Autism Spectrum Disorder have highly variable lower extremity walking patterns, yet, this has not been sufficiently quantified. As such, the purpose of this study was to examine walking pattern variability by way of lower extremity coordination and spatio-temporal characteristics in children with autism compared with individuals with typical development during over-ground walking.

methodsBilateral continuous relative phase variability was computed for the thigh-leg, leg-foot, and thigh-foot segment couples for 11 children with autism and 9 children with typical development at each gait sub-phase. Furthermore, left and right stride lengths and stride width were computed and compared. The Model Statistic was utilized to test for statistical differences in variability between each child with autism to an aggregate group with typical development. Effect sizes were computed to determine the meaningfulness between responses for children with autism and typical development. Coefficient of variation and effect sizes were computed for stride lengths and stride width.

findingsAnalysis revealed that children with autism exhibited differences in variability in each gait sub-phase. Notably, all but two children with autism exhibited lesser variability in all segment couples during terminal swing. Differences in stride lengths were relatively minimal, however, greater coefficient of variation magnitudes in stride width were observed in children with autism.

interpretationThis finding reveals that children with autism may have limited or a preferred movement strategy when preparing the foot for ground contact. The findings from this study suggest variability may be an identifiable characteristic during movement in children with autism.

Indexed as

Mechanical PhenomenaWalkingAutism Spectrum DisorderBiomechanical PhenomenaChildFemaleGaitHumansLower ExtremityMaleModels, StatisticalBiomechanicsCoefficient of variationKinematicsLocomotionPediatrics

Identifiers

PMID32408186
PMCPMC7282997

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.