Evidence map›Paper›PMID 32408174›Full record

ArticleiScience2020

Non-canonical Eclosion Hormone-Expressing Cells Regulate Drosophila Ecdysis.

Robert L Scott, Fengqiu Diao, Valeria Silva, Sanghoon Park, Haojiang Luan, John Ewer, Benjamin H White

Open access · goldAbstract read
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Key Neuropeptides Regulating Molting in Pacific White Shrimp (Animals : an open access journal from MDPI · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Completion of metamorphosis after adult emergence inCurrent research in insect science · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Robert L ScottLaboratory of Molecular Biology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Fengqiu DiaoLaboratory of Molecular Biology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Valeria SilvaCentro Interdisciplinario de Neurociencia, Universidad de Valparaiso, Playa Ancha, Valparaiso, CHILE.
Sanghoon ParkLaboratory of Molecular Biology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Haojiang LuanLaboratory of Molecular Biology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
John EwerCentro Interdisciplinario de Neurociencia, Universidad de Valparaiso, Playa Ancha, Valparaiso, CHILE.
Benjamin H WhiteLaboratory of Molecular Biology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA. Electronic address: benjaminwhite@mail.nih.gov.
National Institute of Mental Health · USValparaiso University · US

Funding

Identifying Neural Substrates of Behavior in Drosophila MelanogasterZIAMH002800 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI WHITE, BENJAMIN H · 2009 to 2025
$29.2M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Intramural NIH HHS ZIA MH002800NIH HHS P40 OD018537
6 · The paper itself

Abstract

Eclosion hormone (EH) was originally identified as a brain-derived hormone capable of inducing the behavioral sequences required for molting across insect species. However, its role in this process (called ecdysis) has since been confounded by discrepancies in the effects of genetic and cellular manipulations of EH function in Drosophila. Although knock-out of the Eh gene results in severe ecdysis-associated deficits accompanied by nearly complete larval lethality, ablation of the only neurons known to express EH (i.e. V

Indexed as

Biological SciencesDevelopmental BiologyDevelopmental Neuroscience

Identifiers

PMID32408174
PMCPMC7225733
OpenAlexW3019094820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.