ArticleJournal of veterinary internal medicine2020
Cytological and microbiological characteristics of middle ear effusions in brachycephalic dogs.
Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Prevalence of incidental and causative otitis in 380 client-owned dogs undergoing brain magnetic resonance imaging for signs of vestibular and non-vestibular disease.Journal of veterinary internal medicine · 2026Article
- Mid- to long-term outcomes of the surgical treatment of 20 middle ear cholesteatomas in 18 French bulldogs.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2026Article
- Quantitative genetic analysis of respiratory function and related traits in Bulldogs, French Bulldogs and Pugs.PloS one · 2026Article
- Fluoroscopic guidance for bulla identification during ventral bulla osteotomy in eight French bulldogs.Veterinary record open · 2025Article
- Otogenic Meningitis or Meningoencephalitis in 30 Dogs: Association Between Neurological Signs, Magnetic Resonance Imaging Findings, and Outcome.Veterinary sciences · 2025Article
- Quantitative evaluation of middle ear radiopacity in French bulldogs using X-ray imaging.Open veterinary journal · 2024Article
- Short- and long-term outcomes of subtotal ear canal ablation and lateral bulla osteotomy in French bulldogs.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2023Article
- The Middle Ear Microbiota in Healthy Dogs Is Similar to That of the External Ear Canal.Veterinary sciences · 2023Article
- Phenotypic characterization of Pomeranians with or without Chiari-like malformation and syringomyelia.Frontiers in veterinary science · 2023Article
- Brachycephalic obstructive airway syndrome: much more than a surgical problem.The veterinary quarterly · 2022Review
- Cytological and microbiological characteristics of middle ear effusions in brachycephalic dogs.Journal of veterinary internal medicine · 2020Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMiddle ear effusion is common in brachycephalic dogs with similarities to otitis media with effusion in children. Association with the cranial and eustachian tube morphology and bacterial infection is suspected in both species. HYPOTHESIS/
objectivesTo determine cytological and bacteriological features of middle ear effusions in dogs, provide information on histological features, and further assess the dog as a model of the human disease. ANIMALS: Sixteen live dogs, 3 postmortem cases of middle ear effusion, and 2 postmortem controls.
methodsProspective; clinical investigation using computed tomography, magnetic resonance imaging, video-otoscopy, myringotomy; cytological assessment of 30 and bacteriology of 28 effusions; histology and immunohistochemistry (CD3 for T-lymphocytes, Pax5 for B lymphocytes and MAC387 for macrophages) of 10 middle ear sections.
resultsEffusions were associated with neurological deficits in 6/16 (38%) and concurrent atopic dermatitis and otitis externa in 9/16 (56%) of live cases. Neutrophils and macrophages predominated on cytology (median 60 [range 2%-95.5%] and 27 [2%-96.5%]) whether culture of effusions was positive or not. In histology sections, the mucosa was thickened in affected dogs but submucosal gland dilatation occurred in affected and unaffected dogs. There was no bacterial growth from 22/28 (79%) of effusions. Bacteria isolated from the other 6 (21%) were predominantly Staphylococcus pseudintermedius (4/6, 67%). CONCLUSIONS AND CLINICAL IMPORTANCE: Clinical, morphological, and cytological findings in middle ear effusions of dogs and people suggest similar pathogeneses. Middle ear effusion of dogs could be a useful model of human otitis media with effusion. Such comparisons can improve understanding and management across species.
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