Evidence map›Paper›PMID 32407425›Full record

ArticleDalton transactions (Cambridge, England : 2003)2020

Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging.

Thines Kanagasundaram, Carsten S Kramer, Eszter Boros, Klaus Kopka

Open access · greenAbstract read
In one paragraph

Article in Dalton transactions (Cambridge, England : 2003), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 5 countries.

Thines KanagasundaramDivision of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 223, 69120 Heidelberg, Germany and Institute of Inorganic Chemistry, Heidelberg University, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.ORCID http://orcid.org/0000-0001-8265-8591
Carsten S KramerDivision of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 223, 69120 Heidelberg, Germany.ORCID http://orcid.org/0000-0001-9932-423X
Eszter BorosDepartment of Chemistry, Stony Brook University, 100 Nicolls Road, Stony Brook, New York 11790, USA. eszter.boros@stonybrook.edu.ORCID http://orcid.org/0000-0002-4186-6586
Klaus KopkaHelmholtz-Zentrum Dresden-Rossendorf (HZDR) e.V., Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany. k.kopka@hzdr.de.ORCID http://orcid.org/0000-0003-4846-1271
German Cancer Research Center · DEHelmholtz-Zentrum Dresden-Rossendorf · DEStony Brook Medicine · US

Funding

Development of Zr-89 based immunoPET agents for idiopathic pulmonary fibrosisR00HL125728 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI BOROS, ESZTER · 2018 to 2020
$744k
NHLBI NIH HHS R00 HL125728
6 · The paper itself

Abstract

Fluorescent Si-rhodamines were modified to enable complexation with the Re(i)- and 99mTc(i)-tricarbonyl core. The corresponding complexes exhibit suitable properties as bimodal imaging probes for SPECT- and optical imaging in vitro. Importantly, the novel in- aqueous-solution-stable, functionalized Si-rhodamines retain favourable optical properties after complexation (QY = 0.09, λabs = 654 nm, λem = 669 nm in PBS) and show promising near-infrared optical properties for potential in vivo applications enabling bimodal scintigraphic imaging and optical imaging, e.g. used in radio- and fluorescence-guided tumour resection.

Identifiers

PMID32407425
PMCPMC9161823
OpenAlexW3023641421

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.