ArticlePloS one2020
Identification of a new R3 MYB type repressor and functional characterization of the members of the MBW transcriptional complex involved in anthocyanin biosynthesis in eggplant (S. melongena L.).
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.
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28 citing papers in PubMed, 43 citations in OpenAlex.
- AaMYB114 promotes the coloration of Actinidia arguta by synthesizing and transporting anthocyanins.BMC plant biology · 2026Article
- Transcriptomic landscapes of tissue-specific color transition in eggplant reveal regulatory roles of lncRNAs and alternative splicing in anthocyanin biosynthesis.Frontiers in plant science · 2026Article
- Resequencing and phenotyping of the first highly inbred eggplant multiparent population revealHorticulture research · 2025Article
- Molecular mechanisms driving the unusual pigmentation shift during eggplant fruit development.Plant communications · 2025Article
- Comparative Transcriptomic Analyses of Anthocyanin Biosynthesis Genes in Eggplant Under Low Temperature and Weak Light.Plants (Basel, Switzerland) · 2025Article
- Association analyses reveal both anthropic and environmental selective events during eggplant domestication.The Plant journal : for cell and molecular biology · 2025Article
- Genetic and Biotechnological Approaches to Improve Fruit Bioactive Content: A Focus on Eggplant and Tomato Anthocyanins.International journal of molecular sciences · 2024Review
- Genomic and transcriptomic studies on flavonoid biosynthesis in Lagerstroemia indica.BMC plant biology · 2024Article
- Cloning ofInternational journal of molecular sciences · 2023Article
- Genome-Wide Identification of theInternational journal of molecular sciences · 2023Article
- A Compendium for Novel Marker-Based Breeding Strategies in Eggplant.Plants (Basel, Switzerland) · 2023Review
- Cyanidin-3-O-glucoside Contributes to Leaf Color Change by Regulating TwoInternational journal of molecular sciences · 2023Article
- Characterization of Highbush Blueberry (Current issues in molecular biology · 2023Article
- Flavonoids - flowers, fruit, forage and the future.Journal of the Royal Society of New Zealand · 2023Review
- High temperature inhibited the accumulation of anthocyanin by promoting ABA catabolism in sweet cherry fruits.Frontiers in plant science · 2023Article
- Construction of a High-Density Recombination Bin-Based Genetic Map Facilitates High-Resolution Mapping of a Major QTL Underlying Anthocyanin Pigmentation in Eggplant.International journal of molecular sciences · 2022Article
- Integrating Transcriptomic and Metabolomic Analyses to Explore the Effect of Color Under Fruit Calyx on That of Fruit Apex in Eggplant (Frontiers in genetics · 2022Article
- Insights Into the MYB-Related Transcription Factors Involved in Regulating Floral Aroma Synthesis in Sweet Osmanthus.Frontiers in plant science · 2022Article
- Newly Developed MAGIC Population Allows Identification of Strong Associations and Candidate Genes for Anthocyanin Pigmentation in Eggplant.Frontiers in plant science · 2022Article
- Mutations in theFrontiers in plant science · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here we focus on the highly conserved MYB-bHLH-WD repeat (MBW) transcriptional complex model in eggplant, which is pivotal in the transcriptional regulation of the anthocyanin biosynthetic pathway. Through a genome-wide approach performed on the recently released Eggplant Genome (cv. 67/3) previously identified, and reconfirmed by us, members belonging to the MBW complex (SmelANT1, SmelAN2, SmelJAF13, SmelAN1) were functionally characterized. Furthermore, a regulatory R3 MYB type repressor (SmelMYBL1), never reported before, was identified and characterized as well. Through a qPCR approach, we revealed specific transcriptional patterns of candidate genes in different plant tissue/organs at two stages of fruit development. Two strategies were adopted for investigating the interactions of bHLH partners (SmelAN1, SmelJAF13) with MYB counterparts (SmelANT1, SmelAN2 and SmelMYBL1): Yeast Two Hybrid (Y2H) and Bimolecular Fluorescent Complementation (BiFC) in A. thaliana mesophylls protoplast. Agro-infiltration experiments highlighted that N. benthamiana leaves transiently expressing SmelANT1 and SmelAN2 showed an anthocyanin-pigmented phenotype, while their co-expression with SmelMYBL1 prevented anthocyanin accumulation. Our results suggest that SmelMYBL1 may inhibits the MBW complex via the competition with MYB activators for bHLH binding site, although this hypothesis requires further elucidation.
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