Evidence map›Paper›PMID 32406505›Full record

ArticleChemical senses2020

Odor Sensitivity Versus Odor Identification in Older US Adults: Associations With Cognition, Age, Gender, and Race.

Lucy Xu, Jia Liu, Kristen E Wroblewski, Martha K McClintock, Jayant M Pinto

Open access · bronzeAbstract read
In one paragraph

Article in Chemical senses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Serum vitamin D levels and olfactory function in adults: a cross-sectional study with dose-response and ROC analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Article
  5. Article
  6. Age-related decrease of odorant sensitivity for a selection of nine diverse molecules.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  7. Article
  8. Article
  9. Sensory Health Among Older Adults in the United States: A Neighborhood Context Approach.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  10. Normative Data for the 12-Item Sniffin' Sticks Odor Identification Test in Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Article
  11. Article
  12. Olfactory Dysfunction and Depression Trajectories in Community-Dwelling Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  13. Article
  14. Intranasal insulin for COVID-19-related smell loss.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  15. Evaluating long-term smell or taste dysfunction in mildly symptomatic COVID-19 patients: a 3-year follow-up study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Observational
  16. Association ofNeurology · 2023
    Article
  17. The Association of Peripheral and Central Olfaction With Frailty in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lucy XuPritzker School of Medicine, The University of Chicago, Chicago, USA.
Jia LiuBeijing An Zhen Hospital, Capital Medical University, An Zhen Hospital, Beijing, China.
Kristen E WroblewskiDepartment of Public Health Sciences, The University of Chicago, Chicago, USA.
Martha K McClintockDepartment of Comparative Human Development, The University of Chicago, Chicago, USA.
Jayant M PintoSection of Otolaryngology, Head and Neck Surgery, The University of Chicago, Chicago, USA.
University of Chicago · USBeijing Anzhen Hospital · CNChicago Department of Public Health · US

Funding

National Social Life, Health, and Aging Project: Round 5R01AG048511 · NIA · NATIONAL OPINION RESEARCH CENTER · PI LINDA J WAITE · 2014 to 2026
$49.5M
National Social Life, Health and Aging: Wave 4R01AG043538 · NIA · NATIONAL OPINION RESEARCH CENTER · PI LINDA J WAITE · 2013 to 2026
$42.7M
National Social Life, Health, and Aging Project: Anaylsis of Wave 1 and Wave 2R37AG030481 · NIA · NATIONAL OPINION RESEARCH CENTER · PI WAITE, LINDA J · 2008 to 2017
$15.4M
SPECIALIZED TRAINING PROGRAM IN THE DEMOGRAPHY &ECON.T32AG000243 · NIA · UNIVERSITY OF CHICAGO · PI DAVID O MELTZER · 1994 to 2026
$8.2M
Particulate matter-induced changes in DNA methylome and transcriptomeU01ES026718 · NIEHS · UNIVERSITY OF CHICAGO · PI MUTLU, GOKHAN M. · 2016 to 2019
$2.5M
Short Term Aging-Related Research ProgramT35AG029795 · NIA · UNIVERSITY OF CHICAGO · PI Vineet Arora, DAVID O MELTZER · 2008 to 2026
$1.4M
NIA NIH HHS R01 AG043538NIA NIH HHS R01 AG048511NIA NIH HHS R37 AG030481NIA NIH HHS T32 AG000243NIA NIH HHS T35 AG029795NIEHS NIH HHS U01 ES026718
6 · The paper itself

Abstract

The ability to identify odors predicts morbidity, mortality, and quality of life. It varies by age, gender, and race and is used in the vast majority of survey and clinical literature. However, odor identification relies heavily on cognition. Other facets of olfaction, such as odor sensitivity, have a smaller cognitive component. Whether odor sensitivity also varies by these factors has not been definitively answered. We analyzed data from the National Social Life, Health, and Aging Project, a nationally representative study of older US adults (n = 2081). Odor identification was measured using 5 validated odors presented with Sniffin' Stick pens as was odor sensitivity in a 6-dilution n-butanol constant stimuli detection test. Multivariate ordinal logistic regression modeled relationships between olfaction and age, gender, race, cognition, education, socioeconomic status, social network characteristics, and physical and mental health. Odor sensitivity was worse in older adults (P < 0.01), without gender (P = 0.56) or race (P = 0.79) differences. Odor identification was also worse in older adults, particularly men (both P ≤ 0.01), without differences by race. Decreased cognitive function was associated with worse odor identification (P ≤ 0.01) but this relationship was weaker for odor sensitivity (P = 0.02) in analyses that adjusted for other covariates. Odor sensitivity was less strongly correlated with cognitive ability than odor identification, confirming that it may be a more specific measure of peripheral olfactory processing. Investigators interested in associations between olfaction and health should consider both odor sensitivity and identification when attempting to understand underlying neurosensory mechanisms.

Indexed as

CognitionOdorantsAgedAge FactorsCross-Sectional StudiesEconomic FactorsFemaleHumansMaleMental HealthMiddle AgedQuality of LifeRace FactorsSex FactorsSmellSocial Networkingagingcognitionepidemiologyodor identificationodor sensitivitysocial network

Identifiers

PMID32406505
PMCPMC7320224
OpenAlexW3024140665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.