Evidence map›Paper›PMID 32406502›Full record

ArticleBioscience reports2020

Identification of hub genes related to prognosis in glioma.

Delong Zhang, Jinxia Zhao, Chengzheng Han, Xiaocen Liu, Jun Liu, Hui Yang

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Delong ZhangKey Laboratory of Non-coding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), Wuhu 241001, Anhui, People's Republic of China.
Jinxia ZhaoDepartment of Anesthesiology, The First Affiliated Hospital of Wannan Medical College, Wuhu 241001, Anhui, People's Republic of China.
Chengzheng HanClinic of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu 241001, Anhui, People's Republic of China.
Xiaocen LiuDepartment of Nuclear Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu 241001 Anhui, People's Republic of China.
Jun LiuDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu 241001, Anhui, People's Republic of China.
Hui YangKey Laboratory of Non-coding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), Wuhu 241001, Anhui, People's Republic of China.
First Affiliated Hospital of Wannan Medical College · CNWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma, a common malignant tumor of the central nervous system, has high invasiveness. The objective of the present study was to identify genes playing an important role in the development of glioma and to reveal their potential research value. Conjoint analysis on the GSE16011 dataset in the Gene Expression Omnibus (GEO) database and the 'Messenger RNA Expression Microarray of Diffuse Gliomas and Controls' dataset and 'RNA sequencing of Diffuse Gliomas' dataset in the Chinese Glioma Genome Atlas (CGGA) database is carried out in the study. The weighted correlation network analysis (WGCNA) was used to carry out co-expression analysis on the GSE16011. Finally, 24 genes significantly related to grade and prognosis were obtained. In addition, there is no report about CACNG2, JPH3, TUBB6 (tubulin β 6 class V), NRSN1, FAM19A2, NALCN, CDH18, GNAL on glioma.

Indexed as

TranscriptomeAdultAgedAged, 80 and overBiomarkers, TumorBrain NeoplasmsDatabases, GeneticFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticGene Regulatory NetworksGenetic Predisposition to DiseaseGliomaHumansMaleMiddle AgedBiomarkers, Tumorbioinformaticsgeneglioma

Identifiers

PMID32406502
PMCPMC7253401
OpenAlexW3025367437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.