ArticleCerebral cortex (New York, N.Y. : 1991)2020
Transient Arousal Modulations Contribute to Resting-State Functional Connectivity Changes Associated with Head Motion Parameters.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Sleep deprivation exhibits an age-dependent effect on infraslow global brain activity.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Global cortical arousal effects in fMRI reveal brain markers of state and trait anxiety.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Stable individualized brain computing model informed by spatiotemporal co-activity patterns.PLoS computational biology · 2025Article
- Patterns of pathological tau deposition reflect the dynamics of cortical brain activity.Cell reports · 2025Article
- Global brain activity and its coupling with cerebrospinal fluid flow is related to tau pathology.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Sex-specific age-related differences in cerebrospinal fluid clearance assessed by resting-state functional magnetic resonance imaging.NeuroImage · 2024Article
- Resting-state global brain activity induces bias in fMRI motion estimates.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Resting-state global brain activity affects early β-amyloid accumulation in default mode network.Nature communications · 2023Article
- Development of neonatal brain functional centrality and alterations associated with preterm birth.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The association between head motion during functional magnetic resonance imaging and executive functioning in older adults.Neuroimage. Reports · 2022Article
- A Multi-Dataset Evaluation of Frame Censoring for Motion Correction in Task-Based fMRI.Aperture neuro · 2022Article
- Test-Retest Reliability of Synchrony and Metastability in Resting State fMRI.Brain sciences · 2021Article
- Single-neuron firing cascades underlie global spontaneous brain events.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Decoupling of Global Brain Activity and Cerebrospinal Fluid Flow in Parkinson's Disease Cognitive Decline.Movement disorders : official journal of the Movement Disorder Society · 2021Article
- Imaging the temporal dynamics of brain states with highly sampled fMRI.Current opinion in behavioral sciences · 2021Article
- Brain Activity Fluctuations Propagate as Waves Traversing the Cortical Hierarchy.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Global waves synchronize the brain's functional systems with fluctuating arousal.Science advances · 2021Article
- Reduced coupling between cerebrospinal fluid flow and global brain activity is linked to Alzheimer disease-related pathology.PLoS biology · 2021Article
- Vigilance Effects in Resting-State fMRI.Frontiers in neuroscience · 2020Review
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4 authors.
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Abstract
Correlations of resting-state functional magnetic resonance imaging (rsfMRI) signals are being widely used for assessing the functional brain connectivity in health and disease. However, an association was recently observed between rsfMRI connectivity modulations and the head motion parameters and regarded as a causal relationship, which has raised serious concerns about the validity of many rsfMRI findings. Here, we studied the origin of this rsfMRI-motion association and its relationship to arousal modulations. By using a template-matching method to locate arousal-related fMRI changes, we showed that the effects of high motion time points on rsfMRI connectivity are largely due to their significant overlap with arousal-affected time points. The finding suggests that the association between rsfMRI connectivity and the head motion parameters arises from their comodulations at transient arousal modulations, and this information is critical not only for proper interpretation of motion-associated rsfMRI connectivity changes, but also for controlling the potential confounding effects of arousal modulation on rsfMRI metrics.
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