ArticleIET systems biology2020
Various skin impedance models based on physiological stratification.
Article in IET systems biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Applications of bioimpedance measurement in clinical and allied fields: a comprehensive review.Biomedical engineering online · 2026Review
- Continuous biosignal acquisition beyond the limit of epidermal turnover.Materials horizons · 2025Review
- Confounding Factors and Their Mitigation in Measurements of Bioelectrical Impedance at the Skin Interface.Bioengineering (Basel, Switzerland) · 2025Review
- Impedance Characterization and Modeling of Gold, Silver, and PEDOT:PSS Ultra-Thin Tattoo Electrodes for Wearable Bioelectronics.Sensors (Basel, Switzerland) · 2025Article
- A clinically interpretable model derived from skin conductance for assessing microangiopathy of the skin surface.NPJ digital medicine · 2025Article
- On the Breathability of Epidermal Polymeric-Printed Tattoo Electrodes.ACS applied electronic materials · 2025Article
- Wearable battery-free chip-less patch for bioimpedance measurement of cutaneous lesions.npj biomedical innovations · 2025Article
- Detecting and monitoring incontinence associated dermatitis: Does impedance spectroscopy have a part to play?Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2024Review
- Practice Guidelines for Monitoring Neuromuscular Blockade-Elements to Change to Increase the Quality of Anesthesiological Procedures and How to Improve the Acceleromyographic Method.Journal of clinical medicine · 2024Review
- Multichannel microneedle dry electrode patches for minimally invasive transdermal recording of electrophysiological signals.Microsystems & nanoengineering · 2024Article
- Using electrocardiogram electrodes to monitor skin impedance spectroscopic response when skin is subjected to sustained static pressure.Skin health and disease · 2023Article
- A review of bio-impedance devices.Medical & biological engineering & computing · 2023Review
- Estimation of skin impedance models with experimental data and a proposed model for human skin impedance.IET systems biology · 2020Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transdermal drug delivery is a non-invasive method of drug administration. However, to achieve this, the drug has to pass through the complicated structure of the skin. The complex structure of skin can be modelled by an electrical equivalent circuit to calculate its impedance. In this work, the transfer function of three electrical models of the human skin (Montague, Tregear and Lykken Model) based on physiological stratification are analysed. Sensitivity analysis of these models is carried out to consider the extent to which changes in system parameters (different types of R and C as described by different models) affect the behaviour of the model. Techniques like normal of derivative and Hausdorff Distance is also used to study and understand the different curves. Comparison is also made with CPE based model. As Montague Model is the most widely used model, Tregear and Lykken Model are compared with it. It can be commented that out of the above observations Tregear Model at Level 3 can be used for establishing the electrical equivalent of human skin due to its simplicity. However, fractional ordered CPE models provide a good approximation. Future prospect lies in developing a model that characterize both biological properties and physiological stratification.
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