Evidence map›Paper›PMID 32406312›Full record

Trial reportJournal of the American Heart Association2020

High Salt Intake Augments Blood Pressure Responses During Submaximal Aerobic Exercise.

Matthew C Babcock, Austin T Robinson, Kamila U Migdal, Joseph C Watso, Christopher R Martens, David G Edwards, Linda S Pescatello, William B Farquhar

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05545501 narecruitingnot on this mapstarted 2023, after this paper: background citation

Ketone Supplementation as a Strategy to Reduce the Negative Health Effects of High Dietary Salt in Young Adults

TypeinterventionalSponsorIndiana UniversityRan2023 to 2027Enrolled35ConditionsSalt, Excess, HypertensionArmsNo Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
NCT06868719 narecruitingnot on this mapstarted 2025, after this paper: background citation

Ketone Supplementation as a Strategy to Reduce the Negative Health Effects of High Dietary Salt in Older Adults

TypeinterventionalSponsorIndiana UniversityRan2025 to 2027Enrolled35ConditionsSalt, Excess, Hypertension, AgingArmsNo Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
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  7. Can We Protect Our Hearts by Sweating Out Excess Sodium?Exercise and sport sciences reviews · 2026
    Review
  8. Relationship Between Salt Intake and Cardiovascular Disease.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. The damaging duo: Obesity and excess dietary salt contribute to hypertension and cardiovascular disease.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  16. Article
  17. Article
  18. Commentaries on Viewpoint: COVID-19 controls causing a kerfuffle.Journal of applied physiology (Bethesda, Md. : 1985) · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Matthew C BabcockDepartment of Kinesiology and Applied Physiology University of Delaware Newark DE.
Austin T RobinsonDepartment of Kinesiology and Applied Physiology University of Delaware Newark DE.
Kamila U MigdalDepartment of Kinesiology and Applied Physiology University of Delaware Newark DE.
Joseph C WatsoDepartment of Kinesiology and Applied Physiology University of Delaware Newark DE.
Christopher R MartensDepartment of Kinesiology and Applied Physiology University of Delaware Newark DE.
David G EdwardsDepartment of Kinesiology and Applied Physiology University of Delaware Newark DE.
Linda S PescatelloDepartment of Kinesiology University of Connecticut Storrs CT.
William B FarquharDepartment of Kinesiology and Applied Physiology University of Delaware Newark DE.
University of Delaware · USUniversity of Connecticut · US

Funding

Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI FANCHER, IBRA · 2016 to 2025
$23.3M
Adverse Neurogenic Actions of Dietary SaltR01HL128388 · NHLBI · UNIVERSITY OF DELAWARE · PI FARQUHAR, WILLIAM B, STOCKER, SEAN D · 2016 to 2019
$2.6M
Racial Differences in Serum Sodium and Blood Pressure RegulationK01HL147998 · NHLBI · TRUSTEES OF INDIANA UNIVERSITY · PI ROBINSON, AUSTIN TYLER · 2019 to 2023
$705k
NHLBI NIH HHS K01 HL147998NHLBI NIH HHS R01 HL128388NIGMS NIH HHS P20 GM113125
6 · The paper itself

Abstract

Background High sodium (Na

Indexed as

Arterial PressureExerciseVasodilationAdultBiomarkersBrachial ArteryDelawareDouble-Blind MethodEndothelium, VascularFemaleHumansMaleNatriuresisNorepinephrineSodium Chloride, DietaryTime FactorsBiomarkersNorepinephrineSodium Chloride, Dietaryacute exerciseblood pressuredietary sodiumexercise pressor reflexflow‐mediated dilation

Identifiers

PMID32406312
PMCPMC7660875
OpenAlexW3024559878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.