Evidence map›Paper›PMID 32406064›Full record

ArticleContact dermatitis2020

Short-term skin reactions following use of N95 respirators and medical masks.

Wei Hua, Ying Zuo, Ruoyu Wan, Lidan Xiong, Jie Tang, Lin Zou, Xiaohong Shu, Li Li

Abstract read
In one paragraph

Article in Contact dermatitis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Compromised skin barrier induced by prolonged face mask usage during the COVID-19 pandemic and its remedy with proper moisturization.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Trial
  5. Risks and benefits of face masks in children.Frontiers in pediatrics · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. N95 respirators alter facial skin physiological functions and lipidome composition in health care personnel.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  10. Effect of Face Masking on Transmission of SARS-CoV-2.Advances in experimental medicine and biology · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Biophysical and biochemical changes in skin health of healthcare professionals using respirators during COVID-19 pandemic.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei HuaDepartment of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-3061-5749
Ying ZuoDepartment of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-4728-0973
Ruoyu WanDepartment of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.
Lidan XiongCosmetic Safety and Efficacy Evaluation Center of West China Hospital, Sichuan University, Chengdu, China.
Jie TangCosmetic Safety and Efficacy Evaluation Center of West China Hospital, Sichuan University, Chengdu, China.
Lin ZouCosmetic Safety and Efficacy Evaluation Center of West China Hospital, Sichuan University, Chengdu, China.
Xiaohong ShuCosmetic Safety and Efficacy Evaluation Center of West China Hospital, Sichuan University, Chengdu, China.
Li LiDepartment of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.

Funding

1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University ZY2016106
6 · The paper itself

Abstract

backgroundIn the context of the COVID-19 pandemic, cases of adverse skin reactions related to the wearing of masks have been observed.

objectivesTo analyze the short-term effects of N95 respirators and medical masks, respectively, on skin physiological properties and to report adverse skin reactions caused by the protective equipment.

methodsThis study used a randomized crossover design with repeated measurements. Twenty healthy Chinese volunteers were recruited. Skin parameters were measured on areas covered by the respective masks and on uncovered skin 2 and 4 hours after donning, and 0.5 and 1 hour after removing the masks, including skin hydration, transepidermal water loss (TEWL), erythema, pH, and sebum secretion. Adverse reactions were clinically assessed, and perceived discomfort and non-compliance measured.

resultsSkin hydration, TEWL, and pH increased significantly with wearing the protective equipment. Erythema values increased from baseline. Sebum secretion increased both on the covered and uncovered skin with equipment-wearing. There was no significant difference in physiological values between the two types of equipment. More adverse reactions were reported following a N95 mask use than the use of a medical mask, with a higher score of discomfort and non-compliance.

conclusionsThis study demonstrates that skin biophysical characters change as a result of wearing a mask or respirator. N95 respirators were associated with more skin reactions than medical masks.

Indexed as

Coronavirus InfectionsPandemicsPneumonia, ViralSkinAdultBetacoronavirusCOVID-19ErythemaFacial DermatosesFemaleHealthy VolunteersHumansHydrogen-Ion ConcentrationMaleMasksMiddle Agedadverse skin reaction, N95 respirator, medical mask, skin biophysical property

Identifiers

PMID32406064
PMCPMC7272965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.