Evidence map›Paper›PMID 32406023›Full record

ArticleJournal of endocrinological investigation2021

BMI modifies the association between serum HDL cholesterol and stroke in a hypertensive population without atrial fibrillation.

Y Yu, L Hu, X Huang, W Zhou, H Bao, X Cheng

Abstract read
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In one paragraph

Article in Journal of endocrinological investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Y YuDepartment of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, Jiangxi, China.
L HuDepartment of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, Jiangxi, China.
X HuangDepartment of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, Jiangxi, China.
W ZhouCenter for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
H BaoDepartment of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, Jiangxi, China. huihui_bao77@126.com.
X ChengDepartment of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, Jiangxi, China. xiaoshumenfan126@163.com.ORCID http://orcid.org/0000-0001-7445-1988
Nanchang University · CN

Funding

Science and Technology Innovation Platform Project of Jiangxi Province 20165BCD41005the National Natural Science Foundation of China 81960074 and 81500233the Project of Jiangxi Outstanding Person Foundation 20192BCBL23024the Projects of the Science and Technology Department, Jiangxi 20171BAB205008the Projects of the Science and Technology Department, Jiangxi 20204237
6 · The paper itself

Abstract

purposeBoth high-density lipoprotein cholesterol (HDL-C) and body mass index (BMI) have an impact on the prevalence of stroke. However, it is unclear whether BMI can modify the relationship between HDL-C and stroke. Therefore, we aimed to assess the effect of the BMI on the association between HDL-C and stroke in a hypertensive population without atrial fibrillation (AF).

methodsWe analyzed data of 10,925 hypertensive patients without AF from the Chinese Hypertension Registry Study. BMI was categorized as < 24 and ≥ 24 kg/m

resultsThe results showed a negative association between HDL-C and stroke in the BMI < 24 kg/m

conclusionsWe found an inverse association between HDL-C and stroke only in the BMI < 24 kg/m

Indexed as

Body Mass IndexAgedBiomarkersCholesterol, HDLFemaleFollow-Up StudiesHumansHypertensionMalePrevalencePrognosisRisk FactorsStrokeBiomarkersCholesterol, HDLAtrial fibrillationBody mass indexHigh-density lipoprotein cholesterolHypertensionStroke

Identifiers

PMID32406023
OpenAlexW3025640778

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.