Evidence map›Paper›PMID 32406018›Full record

ReviewMolecular biology reports2020

Cervical cancer and potential pharmacological treatment with snake venoms.

Alejandro Montoya-Gómez, Leonel Montealegre-Sánchez, Herney Andrés García-Perdomo, Eliécer Jiménez-Charris

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Cells · 2023
    Article
  7. Article
  8. Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alejandro Montoya-GómezGrupo de Nutrición, Facultad de Salud, Universidad del Valle, Calle 4B # 36-00, Edificio 116, Oficina 5002, Cali, Colombia. gabriel.montoya@correounivalle.edu.co.
Leonel Montealegre-SánchezGrupo de Nutrición, Facultad de Salud, Universidad del Valle, Calle 4B # 36-00, Edificio 116, Oficina 5002, Cali, Colombia.ORCID http://orcid.org/0000-0001-7057-717X
Herney Andrés García-PerdomoDepartamento de Cirugía/Urología, Escuela de Medicina, Universidad del Valle, Cali, Colombia.ORCID http://orcid.org/0000-0001-6945-8261
Eliécer Jiménez-CharrisGrupo de Nutrición, Facultad de Salud, Universidad del Valle, Calle 4B # 36-00, Edificio 116, Oficina 5002, Cali, Colombia. eliecer.jimenez@correounivalle.edu.co.ORCID http://orcid.org/0000-0001-6043-1521
Universidad del Valle · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer is the fourth most common cancer worldwide in women. Apoptosis reactivation has become the main strategy for decreasing cancer proliferation. There is a need to extend the search for new drugs to implement more effective and less toxic strategies for cervical cancer treatment. Research has been carried out to find new drugs that have minimal side effects and that focus on the tumor microenvironment, particularly in the induction of cellular apoptosis and cell migration and the inhibition of angiogenesis. Potent toxins from snake venoms have shown potential as sources for the synthesis of new drugs with such characteristics. The present work aimed to describe cervical cancer characteristics, associated risk factors, current treatments and to highlight the effects of toxins isolated from the venom of snakes of the Viperidae family on cervical cancer cell lines.

Indexed as

AnimalsApoptosisCell MovementFemaleHumansNeovascularization, PathologicSnake VenomsToxins, BiologicalTumor MicroenvironmentUterine Cervical NeoplasmsViper VenomsSnake VenomsToxins, BiologicalViper VenomsAnticancer agentApoptosisCytotoxicityToxinsTranslational medicineTumor cell lines

Identifiers

PMID32406018
OpenAlexW3024019106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.