Evidence map›Paper›PMID 32406008›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2020

Functional constipation or redundancy of the colon?

Carmine Noviello, Stefano Nobile, Mercedes Romano, Alessandra Mazzarini, Alfonso Papparella, Giovanni Cobellis

Abstract read
PubMed Publisher
In one paragraph

Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Author's reply to comment on article: Redundant colon and refractory constipation in children.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
    Article
  8. Redundant colon and refractory constipation in children.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
    Article
  9. Editorial commentary on the Indian Journal of Gastroenterology March-April 2020 issue.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Carmine NovielloPediatric Surgery Unit, Salesi Children Hospital, Via Corridoni, 11, 60128, Ancona, Italy. carmine.noviello@libero.it.
Stefano NobileDepartment of Woman and Child Health and Public Health, Division of Neonatology, Fondazione Policlinico Universitario A. Gemelli IRCCS, University Cattolica del Sacro Cuore, Rome, Italy.
Mercedes RomanoPediatric Surgery Unit, Salesi Children Hospital, Via Corridoni, 11, 60128, Ancona, Italy.
Alessandra MazzariniDepartment of Radiological Sciences, Azienda Ospedaliero-Universitaria, Ancona, Italy.
Alfonso PapparellaPediatric Surgery Unit, Università degli Studi della Campania, Luigi Vanvitelli, Naples, Italy.
Giovanni CobellisPediatric Surgery Unit, Salesi Children Hospital, Via Corridoni, 11, 60128, Ancona, Italy.
Azienda Ospedaliero Universitaria Ospedali Riuniti · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesConstipation is a common problem in children, and most of the time, the cause is defined as functional. Our hypothesis is that children with functional refractory constipation had anatomic alterations of the colon.

methodsAll children with chronic refractory constipation who visited our centre underwent accurate clinical examination, contrast enema (CE), anorectal manometry (ARM) and rectal suction biopsies (RSB). In case of functional constipation, three operators measured the size of the colon using radiograms and calculated the ratio based on the width of the second lumbar vertebra. The measurements carried out were compared with those reported in the literature on patients of the same age without constipation.

resultsOver a period of 24 months, 69 patients with chronic refractory constipation, aged between 1 and 14 years, visited our department. A CE was performed on 67, and 2 were excluded because of anal stenosis. Sixty-five underwent anorectal manometry. Rectal suction biopsies were needed in 14 children, and 2 of them were found to have colonic aganglionosis. After a complete evaluation, 57 (82.61%) patients were diagnosed having functional constipation. By comparing the data of the patients with those of normal children reported by the other authors, we found that none of the measurements was statistically significant except for the rectosigmoid length: the mean value in one-year-old patients was 19.03 vs. 9.75, and in older children, it was 19.46 vs. 9.59.

conclusionsRecognizing an anatomic anomaly in patients suffering from functional constipation is important for specific treatment, especially when the ratio (rectosigmoid length/L2) is higher than 15.

Indexed as

AdolescentAge FactorsAnorectal MalformationsBiopsyChildChild, PreschoolChronic DiseaseColonConstipationFemaleHumansInfantMaleManometryRectumRetrospective StudiesAnorectal manometryContrast enemaFunctional constipationRedundancy of the colon

Identifiers

PMID32406008
OpenAlexW3024409773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.