Evidence map›Paper›PMID 32405924›Full record

ReviewLa Radiologia medica2021

Stereotactic Ablative radiation therapy (SABR) for cardiac arrhythmia: A new therapeutic option?

Alba Fiorentino, Fabiana Gregucci, Ilaria Bonaparte, Nicola Vitulano, Alessia Surgo, Rosario Mazzola, Antonio Di Monaco, Roberta Carbonara, Filippo Alongi, Tommaso Langialonga and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

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  2. Linear accelerator-based stereotactic arrhythmia radioablation for paroxysmal atrial fibrillation in elderly: a prospective phase II trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Alba FiorentinoDepartment of Radiation Oncology, General Regional Hospital "F. Miulli", Strada Prov 127, 70021, Acquaviva delle Fonti, Bari, Italy.
Fabiana GregucciDepartment of Radiation Oncology, General Regional Hospital "F. Miulli", Strada Prov 127, 70021, Acquaviva delle Fonti, Bari, Italy. fabianagregucci@gmail.com.
Ilaria BonaparteDepartment of Radiation Oncology, General Regional Hospital "F. Miulli", Strada Prov 127, 70021, Acquaviva delle Fonti, Bari, Italy.
Nicola VitulanoDepartment of Cardiology, General Regional Hospital "F. Miulli", Acquaviva delle Fonti, Bari, Italy.
Alessia SurgoDepartment of Radiation Oncology, General Regional Hospital "F. Miulli", Strada Prov 127, 70021, Acquaviva delle Fonti, Bari, Italy.
Rosario MazzolaDepartment of Radiation Oncology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar-Verona, Italy.
Antonio Di MonacoDepartment of Cardiology, General Regional Hospital "F. Miulli", Acquaviva delle Fonti, Bari, Italy.
Roberta CarbonaraDepartment of Radiation Oncology, General Regional Hospital "F. Miulli", Strada Prov 127, 70021, Acquaviva delle Fonti, Bari, Italy.
Filippo AlongiDepartment of Radiation Oncology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar-Verona, Italy.
Tommaso LangialongaDepartment of Cardiology, General Regional Hospital "F. Miulli", Acquaviva delle Fonti, Bari, Italy.
Massimo GrimaldiDepartment of Cardiology, General Regional Hospital "F. Miulli", Acquaviva delle Fonti, Bari, Italy.
Ospedale Generale Regionale Francesco Miulli · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimStereotactic ablative radiation therapy (SABR) is used in non-oncologic indications, recently even for cardiac arrhythmias. Thus, aim of this analysis is to review preclinical, early clinical evidences and future direction of the latter new treatment approach.

methodA collection of available data regarding SABR and cardiac arrhythmias was made, by Pubmed research and 2 independent researchers, including preclinical and clinical data. A review of ongoing trials was conducted on ClinicalTrials.gov.

resultsPreclinical research conducted in animal models showed that a safe and effective noninvasive treatment approach for cardiac arrhythmias could be represented by SABR with a median time of response around 2-3 months. The treatment dose plays a crucial role: the atrioventricular node would seem more radiosensitive than the other cardiac electric zones. Clinical data, such as published case series, case reports and early prospective studies, have already suggested the feasibility, efficacy and safety of SABR (25 Gy in one session) for refractory ventricular arrhythmias.

conclusionConsidering the ongoing trials of SABR and new technological improvements in radiotherapy (e.g. hybrid magnetic resonance) and in arrhythmias noninvasive mapping systems, the future analyses will improve the reliability of those preliminary results.

Indexed as

Arrhythmias, CardiacHumansRadiosurgeryCardiac ablationCardiac arrhythmiaRadiosurgeryRadiotherapySRS

Identifiers

PMID32405924
OpenAlexW3024037680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.