Evidence map›Paper›PMID 32405898›Full record

ArticleJournal of assisted reproduction and genetics2020

Sperm count affects cumulative birth rate of assisted reproduction cycles in relation to ovarian response.

Carlotta Zacà, Giovanni Coticchio, Nicoletta Tarozzi, Marco Nadalini, Cristina Lagalla, Andrea Garolla, Andrea Borini

Open access · greenAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Carlotta Zacà9.baby - Family and Fertility Center, via Dante 15, 40125, Bologna, Italy.
Giovanni Coticchio9.baby - Family and Fertility Center, via Dante 15, 40125, Bologna, Italy. giovanni.coticchio@nove.baby.ORCID https://orcid.org/0000-0003-1635-9205
Nicoletta Tarozzi9.baby - Family and Fertility Center, via Dante 15, 40125, Bologna, Italy.
Marco Nadalini9.baby - Family and Fertility Center, via Dante 15, 40125, Bologna, Italy.
Cristina Lagalla9.baby - Family and Fertility Center, via Dante 15, 40125, Bologna, Italy.
Andrea GarollaUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, Padova, Italy.
Andrea Borini9.baby - Family and Fertility Center, via Dante 15, 40125, Bologna, Italy.ORCID https://orcid.org/0000-0001-9049-0020
Laboratório Bacchi · BRUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the possible influence of sperm quality, as assessed by prewash total sperm count (TSC), on cumulative success rates in assisted reproduction cycles.

methodsRetrospective study carried out in private IVF centre. Seven hundred sixty-five couples undergoing complete ICSI cycles, i.e. whose all embryos were transferred or disposed of. Couples were characterised by male infertility and female age younger than 36 years. Couples with a combination of female and male infertility factors were excluded. The primary outcome measure was cumulative live birth rate. Secondary outcomes were cumulative pregnancy and miscarriage rates. No specific interventions were made.

resultsHigher TSC values have a positive impact on cumulative success rates in cycles characterised by few retrieved oocytes (1 to 5), while does not influence the outcome of cycles with a normal (6 to 10) or high (> 10) number of retrieved oocytes.

conclusionsThe study highlights the importance of sperm quality for the efficacy of assisted reproduction treatments. This influence may remain relatively cryptic in association with normal or high ovarian response, but emerge decisively in cases of reduced ovarian response, suggesting a relationship between ovarian response and oocyte ability to compensate for paternal-derived deficiencies.

Indexed as

Infertility, MaleSperm CountAdultBirth RateFemaleHumansLive BirthMaleOocyte RetrievalOvulation InductionPregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicSperm-Ovum InteractionsTreatment OutcomeAssisted reproductionLive birthOvarian stimulationPregnancySperm count

Identifiers

PMID32405898
PMCPMC7376993
OpenAlexW3025940101

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.