Evidence map›Paper›PMID 32405806›Full record

ReviewCurrent rheumatology reports2020

Comorbidities of antiphospholipid syndrome and systemic lupus erythematosus in children.

Ummusen Kaya Akca, Nuray Aktay Ayaz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Revisiting Childhood-Onset Systemic Lupus Erythematosus.Turkish archives of pediatrics · 2024
    Article
  4. Platelet-Derived Microparticles and Autoimmune Diseases.International journal of molecular sciences · 2023
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ummusen Kaya AkcaDivision of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Nuray Aktay AyazDivision of Pediatric Rheumatology, Department of Pediatrics, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey. nurayaktay@gmail.com.
Hacettepe University · TRIstanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAntiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases that can affect multiple organ systems. Increased awareness and new treatment strategies ultimately improved the survival of patients, and disease-related comorbidities became more important. The purpose of this review is to focus on comorbidities in these diseases that had a negative influence on the course of the disease. RECENT

findingsThere are limited numbers of studies regarding to comorbidities associated with these diseases during childhood. Infections were found to be the most common comorbidity as a result of immunosuppressive agents and dysregulations of the immune system. Other common comorbidities after infections are cardiovascular and cerebrovascular diseases as important causes of mortality and morbidity. In addition, the risk of malignancies, ophthalmologic manifestations, neurologic and renal diseases, musculoskeletal diseases such as vitamin D deficiency, low bone mineral density, and the risk of avascular necrosis were increased in both patient groups. For clinicians, it is important to be aware of the comorbidities that may develop during follow-up of APS and SLE patients. Further studies will shed more light on the comorbidities of these diseases.

Indexed as

Antiphospholipid SyndromeLupus Erythematosus, SystemicChildComorbidityHumansImmunosuppressive AgentsImmunosuppressive AgentsAntiphospholipid syndromeautoimmune diseasescomorbiditysystemic lupus erythematosus

Identifiers

PMID32405806
OpenAlexW3024926843

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.